Most plastics degradation methods are currently inefficient and are limited by processing difficulties, quality loss and diminished value. This research focuses on the development of novel mechano-chemical disintegration processes for the breakdown of waste plastics. The outputs will be biocatalysed and used as building blocks for new polymers or other bioproducts. For the purpose of this research, microwave pre-treatment technology was used. Microwave technology is an ideal pre-treatment process for degradation of plastics due to its lower treatment times under lower energy inputs. In the previous work, extensive research has been carried out utilizing different solvents and catalysts to develop efficient degradation mechanism under microwave irradiations. A new class of ionic liquids (deep eutectic solvents) was used as catalysts to make suspension with Poly(ethylene terephthalate)PET and develop alcoholysis reaction. Certain degradation parameters like crystallinity index, weight loss, carbonyl index were depicted using DSC, TGA and FTIR characterisation techniques. Furthermore, enhanced enzymatic degradation proved that microwave technology is an efficient process for the alcoholysis reactions and degradation of PET under mild conditions.