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Novel magnetic 4-aminobenzenesulfonic acid-functionalized periodic mesoporous organosilica as a highly efficient and reusable nanocatalyst for the sustainable synthesis of dibenzo[1,4]diazepine derivatives
Published:
14 November 2021
by MDPI
in The 25th International Electronic Conference on Synthetic Organic Chemistry
session Bioorganic, Medicinal and Natural Products Chemistry
https://doi.org/10.3390/ecsoc-25-11796
(registering DOI)
Abstract:
New magnetic 4-aminobenzenesulfonic acid (PABSA)-functionalized periodic mesoporous organosilica (Fe3O4@PMO-ICS-Pr-PABSA) was prepared as a green and recoverable nanocatalyst. This nanocatalyst was able to efficiently catalyze synthesis of dibenzo[1,4]diazepine derivatives via one-pot three-component reactions of o-phenylenediamine, dimedone and various aldehydes at room temperature. This method have the key advantages such as simplicity of operation, high to excellent products yield and short reaction times, easy work-up, accessible catalyst and purification of products by crystallization (non-chromatographic) of this work.
Keywords: Magnetic 4-aminobenzenesulfonic acid-functionalized periodic mesoporous organosilica; dibenzo[1,4]diazepine derivatives; Three-Component reactions; Nanocatalyst.
