The discovery of medicines based on natural products is thriving in the world. India is rich in medicinal plants, which are known to treat various diseases. One among Cardiospermum halicacabum or balloon wine is a climbing plant. It belongs to the family Sapindaceae and it’s known for various pharmacological activities. In total 170 active ingredients were curated from the Collective Molecular Activities of Useful Plants(CMAUP) platform and literature research is funneled for >50% drug-likeness via BIOVIA Discovery studio small molecule tool. The OMIM, Therapeutic Targets database, DrugBank and GeneCard were used to establish a database of breast cancer targets. The interactive compound-gene target was created with Cytoscape software (Version 3.6.1). Further, the protein-protein interaction network was mapped with the STRING database, and the related protein interaction relationship was analyzed. KEGG enrichment and Gene Ontology functional analysis for main drug targets pathways are involved Estrogen signaling pathway, Ras signaling pathway, and Proteoglycans in cancer. Finally, molecular docking of the active ingredients with the primary drug target was carried out. Also, the cell line study was carried out in human breast cancer cell lines MCF7 to investigate the level of cytotoxicity.
Now we closed the publication phase and launched the post-publication phase of the conference. REVIEWWWERS'08 Brainstorming Workshop is Now Open from 2023-Jan-01 to 2023-Jan-31. MOL2NET Committee, Authors, and Validated Social Media Followers Worldwide are ... Invited to Post Moderated Questions/Answers, Comments, about papers. Please kindly post your public Answers (A) to the following questions in order to promote interchange of scientific ideas. These are my Questions (Q) to you:
Q1. Have you considered and/or are you in the process of creating a similar venture with students from your university, using Cardiospermum Halicacabum as a business idea?
Now the conference publication phase is close but you can answer here directly as a post-publication comment. However, in case you want to elaborate your answers in a more structured way in the form of a short communication we can upload it free-of-cost on your behalf to the CATCHTOHIT-03: Congress on Acad. Transl. Res. for Companies Helping to Height. Innov. & Tech., Bilbao-Cambridge, MA, USA, 2022. https://mol2net-08.sciforum.net/catchtohit-03
Thank you for your kind support. Please make questions to other papers in different Mol2Net congresses
Commenting Steps: Login, Go to Papers List, Select Paper, Write Comment, Click Post Comment
Papers list: https://mol2net-08.sciforum.net/presentations/view
Workshop link: https://mol2net-08.sciforum.net/#reviewwwers
