'TaClo', In Vivo Analytic, Disposition and Metabolism of a Chloral-Derived Mammalian Alkaloid With Neurotoxic Properties

G. Bringmann; R. Bruckner; M. Münchbach; D. Feineis; C. Grote; W. Wesemann; S. Diem; M. Herderich

doi:10.3390/ecsoc-4-01894

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'TaClo', In Vivo Analytic, Disposition and Metabolism of a Chloral-Derived Mammalian Alkaloid With Neurotoxic Properties

G. Bringmann

^{*

1},

R. Bruckner

¹,

M. Münchbach

¹,

D. Feineis

¹,

C. Grote

²,

W. Wesemann

²,

S. Diem

³,

M. Herderich

¹ Institute of Organic Chemistry, University of Wurzburg, Am Hubland, D-97074 Wurzburg, Germany.
² Institute of Physiological Chemistry, University of Marburg, Hans-Meerwein-Str., D-35033 Marburg, Germany.
³ Institute of Food Science, University of Wurzburg, Am Hubland, D-97074 Wurzburg, Germany

Published: 11 September 2000 by MDPI in The 4th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products

https://doi.org/10.3390/ecsoc-4-01894

Abstract: According to the toxin hypothesis, reactive chemical compounds (e.g. alkanes, carbolines, cyanides, isoquinolines, heavy metals, pesticides) arising from environmental pollution or drug abuse are discussed to be causative factors for the induction of neurodegenerative processes, e.g. Parkinson's disease.

Keywords: n/a

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