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SYNTHESIS AND IN VIVO IMAGISTIC SKIN EVALUATION OF A NEW DISAZO DYE DERIVED FROM 4,4'-DIAMINOSTILBENE-2,2'- DISULFONIC ACID
Published: 01 November 2009 by MDPI in The 13th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products
Abstract: The synthesis of a new disazo dyes containing 4,4'-diaminostilbene-2,2'-disulfonic acid as middle component is presented. The synthesized dye was analyzed by thin layer chromatography (TLC), electronic spectra (VIS) and HPLC technique. The structure was elucidated by FT/IR and 13CNMR spectroscopy. The colouristic evaluation of the synthesized dye indicates that this dye could be ranged as a direct dye, suitable for application on cellulosic substrates. Further, an in vivo imagistic skin study was performed in order to evaluate the individual human skin tolerance for this new disazo dye.
Keywords: Azo direct dyes, 4, 4’-diaminostilbene-2,2’-disulfonic acid, Colouristic properties, Imagistic skin evaluation