OPTICAL-ELECTRICAL MODULATION OF CORTICAL NEURONAL ACTIVITIES IN THE PERFUSED TISSUE SLICE

Yuki Hayashida

doi:10.3390/optofluidics2017-04580

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OPTICAL-ELECTRICAL MODULATION OF CORTICAL NEURONAL ACTIVITIES IN THE PERFUSED TISSUE SLICE

Yuki Hayashida

¹ Graduate School of Engineering, Osaka University

Published: 21 July 2017 by MDPI in The 7th International Multidisciplinary Conference on Optofluidics 2017 session Other emerging and multidisciplinary researches

https://doi.org/10.3390/optofluidics2017-04580

Abstract:

We here propose a new experimental technique to modulate cortical neuronal activities by a combination of laser light irradiation and electrical microstimulation in the tissue slice perfused with artificial cerebro-spinal fluid. This technique enables one to both excite and inhibit the neuron populations in a spatially confined manner.

Keywords: optical modulation, microstimulation, cerebral cortex, in vitro

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Yuki Hayashida