Some ethyl 6-amino-5-cyano-2-methyl-4-aryl-4H-pyran-3-carboxylates were synthesized by reaction of by using three-component reaction included ethyl acetoacetate, malononitrile and appropriate substituted benzaldehydes. The role of different catalysts was examined, including organic and inorganic substances and ionic liquids. Some 2-amino-4H-pyran-3-carbonitriles were converted by reacting with chloroacetyl chloride. The structures of the obtained compounds were confirmed by the modern spectroscopic methods (IR, 1H NMR, 13C NMR).
Previous Article in event
Next Article in event
SYNTHESIS OF 2-AMINO-4H-PYRAN-3-CARBONITRILES ITS REACTION WITH CHLOROACETYL CHLORIDE
Published: 03 November 2017 by MDPI in The 21st International Electronic Conference on Synthetic Organic Chemistry session Ionic Liquids
Keywords: catalysis, chloroscetyl chloride, ionic liquid, 4H-pyran.