Please login first
SYNTHESIS OF NEW 2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES
* 1, 2, 3 , 1 , 3 , 3
1  Kuban State University
2  ChemEx Lab, Vladimir Dal’ Lugansk National University
3  North Caucasus Federal University

Abstract:

2,2-Dimethyl-5-((phenylamino)methylene)-1,3-dioxane-4,6-dione prepared by reaction of Meldrum’s acid with triethyl orthoformate and aniline, reacts with active methylene nitriles to afford 2-oxo-1,2-dihydropyridine-3-carboxylic acid derivatives useful as drug precursors or perspective ligands.

Keywords: nicotinic acids, Meldrum’s acid, 2-oxo-1,2-dihydropyridine-3-carboxylic acid, cyanothioacetamide, cyanoacetamide.
Top