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Microwave assisted synthesis of bis-heterocycles containing the imidazo[1,2-a]pyridine by Groebke-Blackburn- Bienaymé reaction.
Published:
15 November 2019
by MDPI
in The 23rd International Electronic Conference on Synthetic Organic Chemistry
session Microwave Assisted Synthesis
Abstract:
A serie of six fused bis-heterocycles having imidazo[1,2-a]pyridine frameworks bound with quinoline were synthesized by catalysis and solvent free, microwave assisted Groebke-Blackburn-Bienaymé reaction (GBBR). The synthesis of these compounds is of great interest in synthetic and medicinal chemistry because these heterocycles are considered privileged scaffolds.
Keywords: imidazo[1,2-a]pyridine; Groebke-Blackburn-Bienaymé reaction (GBBR); 2-Chloro-3-formyl-quinoline
