Events The 23rd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session A. General Organic Synthesis of the event The 23rd International Electronic Conference on Synthetic Organic Chemistry

Published date

15 Nov, 2019

Citation

Carlos Zarate Hernández, Manuel Alejandro Rentería Gómez, María Rocío Gámez Montaño, Synthesis of Imidazo[1,2-a]pyridine-chromones via ultrasound-assisted Groebke-Blackburn-Bienaymé Reaction, in Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2019, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-23-06652

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Synthesis of Imidazo[1,2-a]pyridine-chromones via ultrasound-assisted Groebke-Blackburn-Bienaymé Reaction

Carlos Zarate Hernández ¹

Manuel Alejandro Rentería Gómez ¹

María Rocío Gámez Montaño ¹

1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química

Abstract

A serie of imidazo[1,2-a]pyridine-chromones were synthesized by ultrasound-assisted Groebke–Blackburn–Bienaymé reaction (GBBR) under eco-friendly conditions (20 mol% ammonium chloride catalyst in EtOH). Chromones and imidazo[1,2-a]pyridines are a privileged class framework of high interest in medicinal chemistry because they are present in numerous compounds showing relevant biological activities.

Keywords

multicomponent reactions

imidazo[1,2-a]pyridine

GBBR

chromone

green chemistry

Manuscript

ECSOC charly IMP 14 nov.pdf

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