Biomolecules Webinar | Vascular Effects on Neuronal Degeneration and Cognitive Impairment
the chair
Neurodegeneration inevitably leads to cognitive impairment, significantly altering the quality of life of those affected. Neuroinflammatory diseases such as Alzheimer’s disease (AD), multiple sclerosis (MS), traumatic brain injury (TBI), and stroke are associated with memory loss caused by neuronal function impairment. During the past decade, greater attention has been paid to the vascular effects involved in cognitive decline. The topic of vascular cognitive impairment and dementia has been identified as one of the NIH’s research priorities.
Many of these neuroinflammatory responses are associated with changes in the systemic circulation and brain vasculature. Various mechanisms involved in neurodegeneration and cognitive decline stemming from the vasculature have been identified and validated. However, many more questions still remain. The main reason for this is the functional complexity of the neuro-vascular unit and the number of cells that can affect vasculo-neuronal interactions during various neuroinflammatory and neurodegenerative diseases.
Time: 8:00 p.m. CEST | 2:00 p.m. EDT
Webinar ID: 868 0071 2611
Webinar Secretariat: journal.webinar@mdpi.com
Meet the Event Chair
Meet Our Speakers
Dr. Nurul Sulimai
Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL 33612, USA;
Dr. Nurul Sulimai earned her Doctor of Veterinary Medicine degree from University Putra Malaysia in 2009. After practicing as a small animal veterinarian for two years, she obtained her PhD in Veterinary Anesthesia and Analgesia from the Department of Veterinary Clinical Sciences at Purdue University College of Veterinary Medicine in Indiana. Following her doctorate, she worked as a postdoctoral researcher at the University of Virginia in Dr. Joshua Li’s lab, focusing on degenerative intervertebral disc degeneration. Since 2019, she has worked at the Department of Surgery, University of South Florida, as a Research Associate. Her research focuses on the vascular effects on neurodegeneration. Her primary interest is the effect of fibrinogen, as a vascular factor, on neurodegeneration following traumatic brain injury (TBI). In addition, she is also interested in investigations into the inflammatory effects of TBI on cardiovascular complications.
Dr. Andriy Yabluchanskiy
Vascular Cognitive Impairment, Neurodegeneration, and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA;
Dr. Yabluchanskiy’s work is focused on the cardio- and microvascular complications of aging. His unique combination of expertise in neuroscience, cardiovascular pathophysiology, and aging has allowed him to initiate a research program focusing on the understudied and clinically important role of microvascular mechanisms in the development of vascular cognitive impairment. His laboratory utilizes a broad spectrum of techniques including methods to investigate cerebromicrovascular function, measure cerebral blood flow, and characterize cognitive function in animal models of age-related diseases. Recently, Dr. Yabluchanskiy established a Translational Geroscience Laboratory, in which he is currently performing several clinical studies focused on the relationship between neurovascular mechanisms and cognitive impairment in aging and age-related diseases.
Sponsors and Partners
Organizer
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