I would like to welcome you to the Cancers Webinar entitled “Defueling Cancer through Its Metabolic Vulnerabilities: from Basic Science to Therapy”. As I’m sure you are aware, tumor initiation and progression rely on metabolic reprogramming of cancer cells, which exploit various metabolic pathways to address the enhanced bioenergetic and biosynthetic demand required for proliferation and survival. It is noteworthy that tumor cells grow within a specific microenvironment, which metabolically shapes cancer cells to sustain proliferation, invasion, immune evasion and chemoresistance. Many metabolic enzymes and circuits have now been established as cancer vulnerabilities in solid and hematological malignancies, providing new roots for therapeutic intervention.
In this webinar, we will hear from three investigators, Dr. Eugenio Morelli (Dana Farber Cancer Institute), Dr. Giorgia Zadra (National Counsil Research of Italy), and Prof. Mala Shanmugam (Emory Winship Cancer Institute), who will share interesting data on how tumor cells from solid or hematologic malignancies exploit specific, and clinically relevant, metabolic pathways which can be targeted through various approaches to enhance chemosensitivity or promote cell death.
Date: 18 March 2022
Time: 2:30pm CET | 9:30am EDT | 9:30pm CST Asia
Webinar ID: 837 0050 4804
Webinar Secretariat: cancers.webinar@mdpi.com