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4th MMCS: Harnessing the Power of New Drug Modalities

Part of the Molecules Medicinal Chemistry Symposium series
24–26 Apr 2024, Barcelona, Spain
Abstract Submission Deadline
22nd January 2024
Abstract Acceptance Notification
22nd February 2024

Early Bird Registration Deadline
27th February 2024
Covering Author Registration Deadline
11th March 2024
Registration Deadline
13th April 2024

Drug Discovery, Drug Design, Medicinal Chemistry, Molecular Targets
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All abstract acceptance notifications for MMCS 2024 were sent on 22 Feb 2024.
Check your inbox and spam folders. If you can't find them, contact us at mmcs2024@mdpi.com.
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Welcome from the Chairs

Dear Colleagues,

We are delighted to announce the upcoming 4th Molecules Medicinal Chemistry Symposium – Harnessing the Power of New Drug Modalities (MMCS2024), which will take place in Barcelona, Spain, from April 24th to 26th, 2024.

Organized by MDPI, the publisher of the open-access journal Molecules, this conference follows the successful MMCS2019 and MMCS2022 editions, maintaining the highly appreciated three-day format to accommodate a diverse range of contributions and a large audience interested in the impact that the emergence of new drug modalities is having in drug discovery. MMCS2024's thematic sessions will revolve around photoactivatable drugs, candidates that hit RNA and epigenetic targets, and covalent modifiers. The use of these and other more classical approaches for the development of new anti-cancer agents and other medicinal chemistry projects will also be covered.

Each session will include two distinguished invited speakers, who will share their insights alongside selected oral communications. Poster presentations and social events will further enrich the program.

We look forward to welcoming you to Barcelona in April, a perfect time to visit for its delightful weather, vibrant spring atmosphere, and wide array of cultural and outdoor activities that will provide an inspiring backdrop for our conference.

Prof. Diego Muñoz-Torrero
Editor-in-Chief of the Medicinal Chemistry Section of Molecules
MMCS2024 Chair

Prof. Simona Collina
Editorial Board of the Medicinal Chemistry Section of Molecules
MMCS2024 Co-Chair

Conference Secretariat

Dr. Maddalena Favaretto
Ms. Raquel Selles
Dr. Elena González
Email: mmcs2024@mdpi.com

Sponsoring Opportunities

For information regarding sponsorship and exhibition opportunities, please contact us.

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Event Chairs

Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Spain

DETAILS
Bio
Prof. Diego Muñoz-Torrero is Full Professor of Organic and Medicinal Chemistry at the Faculty of Pharmacy and Food Sciences, University of Barcelona (UB). He is Head of the Laboratory of Medicinal Chemistry and belongs to the Governing Board of the Institute of Biomedicine (IBUB). His research focuses on the design and synthesis of new drug candidates against neurodegenerative and parasitic diseases, endowed with innovative mechanisms of action. He belongs to the editorial advisory board of several medicinal chemistry journals and serves as the Editor-in-Chief of the Medicinal Chemistry Section of the MDPI journal Molecules.

Department of Drug Sciences, University of Pavia, Pavia, Italy

DETAILS
Bio
Professor Simona Collina is Head of MedChemLab, Department of Pharmaceutical Sciences, and Dean of the School of Pharmacy at the University of Pavia. Her research activity mainly focuses on the study of chiral compounds and the relationship between absolute configuration and biological activity, and her research interests include design, synthesis of bioactive small molecules, and extraction of secondary metabolites from natural sources, mainly active in neurodegenerative diseases, cancer and pain. She also belongs to the editorial board of Molecules (MDPI), Medicinal Chemistry section.

Event Committee

Department of Pharmacy and Biotechnology, University of Bologna, Italy

DETAILS
Talk
Maria Laura Bolognesi is Professor of Medicinal Chemistry, Coordinator of the Biotechnological, Biocomputational, Pharmaceutical and Pharmacological Sciences PhD Program at the University of Bologna. Her research is concerned with the design, synthesis, and biological investigation of small molecules in the neurodegenerative and neglected tropical disease therapeutic areas. She has a track record of > 200 publications in high-ranked scientific journals, including patents and patent applications, and >100 invited talks worldwide. She was awarded a Distinguished Visiting Professor Fellowship at the Complutense University of Madrid in 2009, a PVE Fellowship at the University of Brasilia in 2014 and Professeur Invité at Université Caen Normandie in 2018. She is also the President of the Medicinal Chemistry Division of the Italian Chemical Society (SCI), an Associate Editor of the Journal of Medicinal Chemistry (ACS) and serves in the Advisory Board of the European Federation of Medicinal Chemistry (EFMC)

Department of Pharmacy, University of Naples Federico II, Italy

DETAILS
Talk
Margherita Brindisi received her PhD from the University of Siena, Italy. In 2010-2011 she worked as a post-doctoral fellow at Purdue University (USA) under the supervision of Prof. Arun K. Ghosh on the development of new antiviral agents and therapeutics for neurodegenerative disorders. From 2012 to 2015 she was appointed as fixed-term Researcher at the University of Siena and in 2016-17 she again moved to Purdue University as a Visiting Researcher. Since April 2019, she was appointed at the Department of Pharmacy of University of Naples Federico II, where she is mainly focusing on the development of novel therapeutic options for infectious and rare diseases. She became an associate Professor at the same Department in April 2022. Margherita is author of 110 publications with more than 3500 citations and inventor of two international patents.
Bio
Margherita Brindisi received her PhD from the University of Siena, Italy. In 2010-2011 she worked as a post-doctoral fellow at Purdue University (USA) under the supervision of Prof. Arun K. Ghosh on the development of new antiviral agents and therapeutics for neurodegenerative disorders. From 2012 to 2015 she was appointed as fixed-term Researcher at the University of Siena and in 2016-17 she again moved to Purdue University as a Visiting Researcher. Since April 2019, she was appointed at the Department of Pharmacy of University of Naples Federico II, where she is mainly focusing on the development of novel therapeutic options for infectious and rare diseases. She became an associate Professor at the same Department in April 2022. Margherita is author of 110 publications with more than 3500 citations and inventor of two international patents.

Institut für Pharmazie und Lebensmittelchemie, University of Würzburg, Germany

DETAILS

Oakland University, USA

DETAILS
Bio
Roman Dembinski obtained his PhD degree at the Centre of Molecular and Macromolecular Studies of the Polish Academy of Sciences, Łódź, with a specialization in organophosphorus chemistry. Following this, he relocated to the University of Utah in Salt Lake City, USA, where he delved into research within the realm of organometallic chemistry, as a research associate under the mentorship of J. A Gladysz. He began his independent career at Oakland University situated in Rochester, Michigan, ultimately achieving the rank of Professor. Professor Dembinski served two terms as chair of Oakland’s Chemistry. He maintains an affiliation with the Center of Biomedical Research. He is also affiliated with the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences. He is currently serving as Editor-in-Chief of Molecules – Organic Chemistry Section. Dembinski has made significant research contributions across various domains, encompassing electrophilic cyclization reactions, the Mitsunobu reaction, fluorous chemistry, organometallic chemistry, nucleoside chemistry, and heterocyclic chemistry.

University of Barcelona & Institute of Biomedicine (IBUB), Spain

DETAILS
Bio
A Full Professor at the Unit of Medicinal Chemistry within the Faculty of Pharmacy and Food Sciences at the University of Barcelona, Prof. Dr. Escolano earned her PhD from the same institution in 1993. Following this, she embarked on a four-month honorary fellowship at the University College of London and pursued a two-year research training contract funded by Marie Curie at Kingston University (UK), focusing on the synthesis of intricate molecules with biological significance. In 2003, she received a Ramon y Cajal contract, and by 2007, she had assumed the role of Associate Professor. Her current research endeavors encompass a wide range of interdisciplinary projects that bridge the fields of chemistry and biology. Her team is dedicated to developing novel chemical entities designed to address pressing healthcare challenges, particularly in areas with significant societal impact, including glioblastoma, neuropathic pain, and neurodegenerative diseases such as Alzheimer's Disease. In her instructional capacity at the Faculty of Pharmacy and Food Sciences, she has been actively engaged in teaching Organic Chemistry and Medicinal Chemistry courses.

Universidad San Pablo CEU, Spain

DETAILS
Bio
Beatriz de Pascual-Teresa is Professor of organic and pharmaceutical chemistry at the Universidad San Pablo CEU. She holds a Doctorate in Pharmacy from the University of Salamanca with top honors. With research training at LSU and UCLA (USA); UAH (Spain), and BASF-AG (Germany), she has been a Professor at CEU San Pablo University since 1996, currently serving as a Professor of Organic and Pharmaceutical Chemistry and is Head of the Department of Chemistry and Biochemistry in the Faculty of Pharmacy. Throughout her career, Prof. de Pascual-Teresa has held various academic roles, including departmental Secretary and Director, and has been the Dean of the Faculty of Pharmacy 2008-2022 and head of the board of Deans of Faculties of Pharmacy from Spain (2018-2022) Her extensive research includes over 25 projects funded nationally and internationally, focusing on active compound design and biological evaluation against diverse pharmacological targets. Prof. de Pascual-Teresa has supervised eight doctoral theses, published 80+ scientific articles, and holds five recognized research six-year periods. As the Director of the Doctoral Program in Health Science and Technology at CEINDO since 2013, Prof. de Pascual-Teresa actively teaches in both undergraduate and postgraduate courses, offering expertise in Pharmacy and Biotechnology in Spanish and English. Beyond academia, her leadership roles in prestigious societies and academies highlight her significant contributions to pharmacy and research fields.

Sapienza University of Rome, Italy

DETAILS
Bio
Rino Ragno is a full professor at the Drug Chemistry and Technology Department - Pharmacy and Medicine Faculty, Sapienza University of Rome. He started as medicinal chemist doing synthesis for about 10 years then as Italian NIH fellow spent two years in the Prof. G. R. Marshall’s lab at Washington University in St. Louis. In 2017 he achieved the national abilitation as Full Professor in medicinal chemistry. Prof. Rino Ragno is co-author of more than 120 peer reviewed articles on international journals at high impact factor.

CERMN, University of Caen Normandy, France

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Bio
Christophe Rochais received his PhD in the group or Prof. S. Rault from the University of Caen Normandie (2005). After a post-doctoral fellowship that he completed in the Centre for Biomolecular Sciences of the University of Nottingham under the supervision of Pr Peter M. Fischer, he was appointed Lecturer in Organic Chemistry in the Faculty of Pharmacy at the University of Caen Normandy in 2007 and since January 2014 he assumed the position of Professor in Organic Chemistry. His research interests include medicinal chemistry program in the field of enzymatic inhibition and receptor modulation in order to develop pharmacological tools and bioactive compounds. Since 2012 he is leading a research program dedicated to the development of pleiotropic agents of interest in the treatment of Alzheimer's disease. In 2022, he was appointed Head of the Centre d’Etudes et de Recherche sur le Médicament de Normandie research group and a member of the French National Academy of Pharmacy.

Grup d'Enginyeria de Materials (GEMAT), Universitat Ramon Llull, Spain

DETAILS

Centro Singular de Investigación en Química Biológica y Materiales Moleculares (CIQUS), University of Santiago de Compostela, Spain

DETAILS
Bio
Eddy Sotelo is a Full Professor of Medicinal Chemistry at the Faculty of Pharmacy of the University of Santiago. He graduated in Chemistry from the University of Havana and earned his Ph.D. at the University of Santiago de Compostela. His postdoctoral experience has been developed through participation in multidisciplinary academic projects and collaborations with the pharmaceutical industry. In 2006, he joined the Institute of Industrial Pharmacy at the University of Santiago de Compostela, where he founded the COMBIOMED group (2008). Eddy is interested in small molecule cancer immunotherapeutics, fluorescent probe development, and proximity-based new drug modalities. His research focuses on pre-clinical drug discovery, particularly the discovery and optimization of NCE using high-throughput synthetic methodologies (https://www.sotelolab.es). Eddy has published over 110 research papers, is inventor of 5 international patents, and participated in the development of six drugs currently undergoing clinical development. Professor Sotelo is deeply committed to collaborative and translational research, he is actively engaging in partnerships with pharmaceutical companies and academic groups and has founded three biotechnological startups. One of these companies, Celtarys Research, specializes in commercializing highly potent and selective fluorescent probes designed for various biomedical applications, such as high-throughput screening (HTS), imaging, and clinical diagnostics.

Laboratory of Organic and Pharmaceutical Chemistry (LQOF), Faculty of Pharmacy, University of Porto, Portugal,
CIIMAR – Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal

DETAILS
Bio
www.ff.up.pt/esousa

University of Innsbruck, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria

DETAILS

Federal University of Alfenas (UNIFAL-MG), Brazil

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Bio
Prof. Claudio Viegas Jr completed his Ph.D. in Chemistry at São Paulo State University in 2003, specializing in Chemistry of Natural Products and Medicinal Chemistry. Since 2022, Prof. Viegas Jr. has been a Full Professor at the Institute of Chemistry at UNIFAL-MG, where he's been involved in undergraduate and postgraduate programs. He leads the Medicinal Chemistry Research Laboratory (PeQuiM) and is dedicated to research in Medicinal Chemistry, focusing on the development of new drug candidates, including those for pain relief, anti-inflammatory, antimicrobial, antiparasitic, antiproliferative, neuroactive, anti-COVID-19, and anti-SARS-COV-2 applications. He is also the leader of the research group "Planning, synthesis, bioprospecting, and characterization of bioactive substances" and a full member of the Brazilian Chemical Society since 1992. Prof. Viegas Jr. is Vice-Coordinator of the Neuroscience League (LINEC) at UNIFAL-MG and collaborates with various foreign institutions on research projects. He serves on the editorial boards of 7 international journals, with an impressive scholarly impact and citations in various databases. Prof. Claudio Viegas Jr. has authored more than 85 papers and four patents in the MedChem field and has been recognized as one of the top scientists worldwide in recent years, according to research and metrics from Stanford University and Elsevier.

Invited Speakers

Faculty of Pharmacy, University of Barcelona, Spain

DETAILS
Bio
Xavier Barril is an ICREA Research Professor at the University of Barcelona, School of Pharmacy. His research focuses on the discovery of bioactive molecules exploiting new mechanisms of action and the development of computational methods to achieve this goal efficiently. He is a well-known expert in the field of structure-based drug discovery, with 100 scientific publications, 40 invited talks at international conferences and 15 supervised Doctoral theses. Prof. Barril has a strong focus on applied research, which has resulted in14 patents, two spin-off companies (Minoryx Therapeutics in 2011 and Oniria Therapeutics in 2021), and active participation in the private drug discovery sector (scientist at Vernalis 2002-2005, part-time CTO at Gain Therapeutics since 2018).

Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, UK

DETAILS
Bio
Paul Brennan received his PhD in organic chemistry from UC Berkeley. Following post-doctoral research at Cambridge University, Paul spent eight years working in the pharmaceutical industry at Amgen and Pfizer. After leaving Pfizer in 2011, Paul joined the Structural Genomics Consortium at the University of Oxford and led the chemical probes discovery effort on epigenetic targets. After leaving the SGC in 2019, Paul was Head of Chemistry and then CSO of the Alzheimer’s Research UK Oxford Drug Discovery Institute where his research was focused on finding new treatments for dementia. Paul is currently Professor of Medicinal Chemistry and Director of the Centre for Medicines Discovery at the University of Oxford. Over the course of his career, Paul has worked on most major drug targets classes: kinases, GPCRs, ion-channels, metabolic enzymes, and epigenetic proteins. His current research is on target validation in neurodegeneration, oncology, virology, and rare diseases; and chemical probe discovery for E3 ligases and small GTPases.

Laboratory of Chemical Biology, Eindhoven University of Technology, The Netherlands

DETAILS
Bio
Luc Brunsveld is professor of Chemical Biology in the Biomedical Engineering department and the Institute for Complex Molecular Systems at the Eindhoven University of Technology. His research centers on chemical biology, particularly protein-protein interaction studies, drug discovery, and supramolecular signaling systems. By melding synthetic and supramolecular chemistry with chemical biology, he achieves precise molecular control over biological systems. The group has cultivated expertise in organic synthesis, peptide and protein chemistry, chemical biology, and supramolecular chemistry, enabling them to craft new molecules and materials for the study, engineering, and modulation of protein-protein interactions. Their ambitions include realizing a synthetic cell and devising novel drugs by fine-tuning protein-protein interactions, ranking high on the group's wish list. Luc is co-founder of Ambagon Therapeutics.

Institute of Chemistry of Nice, Université Côte d'Azur, France

DETAILS
Bio
Dr. Maria Duca is id the CNRS Research Director and Director of the TNA research group at the Institute of Chemistry of Nice (ICN). She holds a Master degree in Pharmaceutical Chemistry from the University of Bologna and a PhD in Molecular Biochemistry from the National Museum of Natural History in Paris. She is Vice-President of the French Medicinal Chemistry Society (SCT) and Associate Editor for RSC Medicinal Chemistry. She also chairs the Chemical Biology Initiative for the European Federation of Medicinal Chemistry, promoting interdisciplinary research. Dr. Duca serves on the Editorial Advisory Board of the Journal of Medicinal Chemistry and the Scientific Advisory Board of ChemMedChem. Recognized for her contributions, Dr. Duca has received prestigious awards, including the Alexandre Joël Award from Fondation ARC and the Michel Delalande Award from the French Pharmacy Academy. Her research focuses on developing synthetic molecules to target oncogenic microRNAs, with publications showcasing innovative approaches.

Department of Chemistry; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, USA

DETAILS
Bio
Prof. Ghosh is the Ian P. Rothwell Distinguished Professor of Chemistry and Medicinal Chemistry at Purdue University. Prof. Ghosh’s research group is involved in multidisciplinary research projects in the areas of synthetic organic, bioorganic, and medicinal chemistry. His group is currently studying critical ligand-binding site interactions of various proteolytic enzymes. This includes cysteine proteases for treatment of COVID-19, BACE1 (memapsin 2), a very significant target for Alzheimer’s disease, as well as, HIV protease whose clinical effectiveness for the treatment of AIDS has been well recognized. Prof. Ghosh created a molecule, known as Darunavir, that in 2006 became the first approved by the Food and Drug Administration to treat drug-resistant HIV. The drug molecule is now approved in 80 countries and is used as a frontline therapy for HIV and AIDS. His groundbreaking research has been recognized with numerous National and International awards, including IUPAC Richter prize, ACS Medicinal Chemistry Hall of Fame, ACS Cope Scholar Award, and MERIT - award from the National Institute of General Medical Sciences.

ICREA, Institute for Bioengineering of Catalonia (IBEC), CIBER-bbn, Spain

DETAILS
Bio
Pau Gorostiza earned his physics degree and European Doctorate in semiconductor electrochemistry at the University of Barcelona (UB). His research at UB's microscopy facility focused on AFM and STM techniques for biological samples and nanotechnology in materials science. He visited CNRS - Université Pierre et Marie Curie in France and the University of California, Berkeley. Currently, an ICREA Research Professor at the Institute for Bioengineering of Catalonia, he develops photoswitchable ligands for neuronal proteins and studies interprotein electron transport in respiratory and photosynthetic complexes with EC-STM/AFM. Notably, he received a HFSP Career Development Award, two ERC grants, published 130 articles (6900 citations, h-index 44), holds 7 patents (5 licensed), and supervised 11 postdoctoral fellows and 13 PhDs.

Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany

DETAILS
Bio
Prof. Dr. Anna Hirsch pursued her education in Natural Sciences with a specialization in Chemistry at the University of Cambridge. During her third year, she had the privilege of studying at the Massachusetts Institute of Technology, where she engaged in a research project alongside Prof. Timothy Jamison. In 2008, she accomplished her Ph.D. from ETH Zurich, concentrating on the de novo structure-based design and synthesis of inhibitors for an anti-infective target enzyme under the supervision of Prof. François Diederich. Subsequently, she undertook an HFSP postdoctoral fellowship at the Institut de Science et d’Ingénierie Supramoléculaires (ISIS) in Strasbourg, led by Prof. Jean-Marie Lehn. She continued then as assistant professor, and afterwards as associate professor, at the Stratingh Institute for Chemistry at the University of Groningen in 2010. In 2017, Anna transitioned to the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), where she serves as the head of the department for drug design and optimization. Her focus remains on anti-infective drug design, employing strategic methods such as structure- and fragment-based drug design. Prof. Hirsch's remarkable achievements have been widely recognized. She received the Gratama Science Prize in 2014, followed by the SCT-Servier Prize for Medicinal Chemistry in 2015. In 2017, her accomplishments were further acknowledged with the Innovation Prize for Medicinal Chemistry by the GdCh/DPhG. Her exceptional contributions earned her the EFMC Young Medicinal Chemist in Academia runner-up Prize in 2019.

The Institute of Cancer Research, London, UK

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Bio
Professor Hoelder is the head of chemistry at the Centre for Cancer Drug Discovery (CCDD), formerly known as Cancer Research UK Cancer Therapeutics Unit, at The Institute of Cancer Research, London. In 2020 he was awarded a professorship in Medicinal Chemistry and Drug Design and in 2022 he became the Head of Chemistry within the CCDD. He completed his PhD in organic chemistry at the Technical University in Berlin in the team of Professor S. Blechert. Following his PhD, Professor Hoelder spent two years in the lab of Professor P.G. Schultz at the University of California, Berkeley establishing methods to identify novel enzymes through selection from large protein libraries. His Post-Doctoral research was supported by a Feodor Lynen Fellowship from the Alexander von Humboldt Foundation. In October 2007, Professor Hoelder joined the faculty of the ICR applying his medicinal chemistry experience to discover novel drugs in the unique and collaborative environment of the Centre for Cancer Drug Discovery (formerly known as Cancer Research UK Cancer Therapeutics Unit). In 2020 he was awarded Professorship in Medicinal Chemistry and Drug Design and in 2022 he became the Head of Chemistry within the Centre for Cancer Drug Discovery.

College of Chemistry and Molecular Engineering, Peking University, China

DETAILS
Bio
Prof. Xiaoguang Lei is the Boya Distinguished Professor of Chemistry and Chemical Biology at the College of Chemistry and Molecular Engineering, Peking University. During his career, he has received numerous prestigious awards including the Molecules 2022 Tu Youyou Award. His laboratory at Peking University conducts research on the interface between chemistry and biology. He focuses on the function-oriented synthesis of structurally complex and bioactive natural products and systematically uses bioactive small molecules (either natural products or unnatural compounds) to study their biological functions, elucidate molecular mechanisms of the essential biological pathways, and develop novel therapeutic agents for currently intractable human diseases, such as cancers and infectious diseases. In addition, he has been exploring the biosynthesis of plant-derived bioactive natural products and developing efficient chemoenzymatic approaches to access these complex molecules. During his career to date, Prof. Dr. Lei has distinguished himself with numerous high-quality contributions in diverse areas of natural product synthesis, chemical biology, and drug discovery. His investigations into the molecular details and mechanisms at the interface between chemistry and biology have led to novel discoveries with potentially significant consequences for molecular medicine.

Istituto Officina dei Materiali (IOM) at International School of Advanced Studies (SISSA), Italy

DETAILS
Bio
Alessandra Magistrato obtained her PhD at ETZ Zuerich, Swizerland, following which she was appointed as postdoc researcher at University of Pennsylvania, Philadelphia PA, USA. In 2003 she became Tenure track at INMF- Democritos simulation center at the International School for Advanced Studies (SISSA), Trieste, Italy. From 2006 she became permanent research staff of CNR-IOM@SISSA where she leads a laboratory of computational biology and biochemistry. Since 2018 she has been Research Director of CNR-IOM at SISSA. Her research interests concern the use of state of the art computational techniques for the study of biological and biochemical systems involved in the onset of human diseases. In particular, her research focuses on drug and protein interactions with nucleic acids RNA, (metal based) enzymatic and RNA catalysis, transport mechanism via ionic channels, role of metals in neurodegenerative diseases.

Groningen Research Institute of Pharmacy, University of Groningen, The Netherlands

DETAILS
Bio
Wiktor Szymanski, was granted his PhD from The Warsaw University of Technology, Poland, in 2008, under the guidance of Prof. Ryszard Ostaszewski. He then honed his expertise in biotransformations in organic chemistry during a two-year period with Prof. Ben L. Feringa and Prof. Dick B. Janssen at the University of Groningen. Since 2010, his focus has centered on creating photoactive protein, peptide, and DNA bioconjugates, delving into the realm of photopharmacology in the Feringa Labs. In 2014, he joined the Medical Imaging Center at the University Medical Center Groningen, eventually obtaining the role of tenure track assistant professor in 2015 and associate professor in 2019. He was appointed full professor in 2023 at the Groningen Research Institute of Pharmacy, where he holds the chair of Medicinal Chemistry, Photopharmacology, and Imaging.

Department of Biomedicine, University of Basel, Switzerland

DETAILS
Bio
Prof. Matthias P. Wymann is at the Department of Biomedicine, University of Basel, investigating the role of class I PI3K isoforms in chronic inflammation, allergy, cancer and metabolism. He introduced wortmannin as the first PI3K inhibitor in 1993, and elucidated its covalent interaction site with PI3Kα and PI3Kγ. The first viable PI3K knock-out mice then established the role of PI3Kγ downstream of G protein-coupled receptor (GPCR) signaling, establishing a mechanism for PI3K-dependent chemokine action on hematopoietic cells. Over the past years, his research has primarily focused on the role of non-redundant functions of PI3Kγ complexes in allergy and metabolism, and the development of PI3K and mTOR-selective inhibitors for cancer therapy. Among these, Bimiralisib/PQR309 reached phase II trials. Chemical probes and covalent PI3Kα inhibitors are currently explored to investigate PI3Kα in metabolism and adverse effects to improve PI3Kα targeted therapy.

Abridged Program

Wednesday 24 April 2024: 13:00-18:30
Thursday 25 April 2024: 09:00-18:00 - Conference Dinner: 20:00
Friday 26 April 2024: 09:00-17:15

Registration


The conference will be held fully in person; it is not possible to participate online. The registration fee includes attendance at all conference sessions, morning/afternoon coffee breaks, lunch, a conference bag, and a program book. Participation in the conference is considered final only once the registration fees have been paid. The number of participants is limited: once the number of paid registrations reaches the maximum number of participants, unpaid registrations will be canceled.

Please note that abstract submission and conference registration are two separate processes. During registration, please provide us with the same email address you used to submit your abstract(s). Otherwise, leave us a comment in the registration form, providing the email address used during the submission process. In addition, please use your institutional email address for both processes. If you are registering several people under the same registration order, please do not use the same email address for each person but their individual institutional email addresses. Thank you for your understanding.

Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as the Covering Author, is required to cover the presentation and publication of any accepted abstract. The Covering Author registration deadline is 10 March 2024. Your abstract will be withdrawn if your registration is not complete by this date.

Group Registration: Groups of five or more attendees are offered a 10% discount on the registration fees. To enjoy this discount, you need to complete one multiple registration by selecting the number of people attending in each category (type of registration) during the first step of the registration process. Please note that no other discounts will be applicable.

Partnering Societies: Members from partnering societies are granted a 20% discount on all registration fees. Please make sure to provide us with proof that you are part of one of our partnering societies. Are you part of a society that isn't partnering with the conference? Contact us to discuss a possible partnership!

Certificate of Attendance: Participants of the event will be able to download an electronic Certificate of Attendance by accessing their dashboards on Sciforum.net once the event is concluded. The certificates will be found under the "My Certificates" category.

Reduced fees

If you are affiliated with a university in a low- or middle-income country, you are automatically eligible for a price reduction. However, please note that the reduced price will only be added to your registration when it is processed. This means that you do not have to pay the stated price immediately upon registration, and you will receive an invoice with the price adjustment after you have registered. Below, you can find the list of low- and middle-income countries.

Early Bird
Until 27th February 2024
Regular
Until 13th April 2024
Supported documents
Academic 500.00 EUR 600.00 EUR
Early Career Researcher (PhD completed within the past five years) 350.00 EUR 450.00 EUR Please include a proof of graduation date (CV, Diploma, University profile page screenshot)
Student 300.00 EUR 400.00 EUR Scanned copy or photograph of your current Student ID Card
Guest Editor/Board Member of Molecules 400.00 EUR 500.00 EUR
Author/Reviewer of Molecules* 450.00 EUR 550.00 EUR *Author or Reviewer in the last 5 years
Non-Academic 800.00 EUR 900.00 EUR
Chairs, Invited Speakers and Committee Members Free Free
Cancellation policy

Cancellation of paid registration is possible under the terms listed below:
> 2 months before the conference Full refund but 60 EUR is retained for administration
> 1 month before the conference Refund 50% of the applying fees
> 2 weeks before the conference Refund 25% of the applying fees
< 2 weeks before the conference No refund

Disclaimer

In the unlikely event that MDPI deems it necessary to cancel the conference, all pre-paid registration fees will be reimbursed. MDPI shall not be liable for reimbursing the cost of travel or accommodation arrangements made by individual delegates.

Beware of unauthorized registration and hotel solicitations

Note that Sciforum is the only official registration platform to register to MMCS2024 and that we are not associated with any hotel agency (other than those listed on the conference website). While other hotel resellers and travel agencies may contact you with offers for your trip, they are not endorsed by or affiliated with MMCS2024 or Sciforum. Beware that entering into financial agreements with non-endorsed companies can have costly consequences.

Insurance

The organizers do not accept liability for personal accident, loss, or damage to private property incurred as a result of participation in The 4th Molecules Medicinal Chemistry Symposium. Delegates are advised to arrange appropriate insurance to cover travel, cancellation costs, medical, and theft or damage of belongings.

MDPI Conference Admissions Policy
  • All registered conference delegates are asked to always wear their badges throughout the conference.
  • Conference sessions, the catering area, and the poster area are solely restricted to badge holders. Any person attending these areas without a badge will be asked to leave the premises.
  • Badge holders must not allow their badges to be worn by anyone else. Any failure to do so is likely to lead to the badge holder and the person wearing the badge being removed from the premises.
  • Press badges are restricted to publishers, editors, journalists, broadcasters, and web bloggers associated with the conference subject area. Members of the press may be asked to produce accreditation in the form of a photocopy of a recognized press or media card, a business card, a letter from the editor, or an official web address linking to a press release in order to verify their position.
  • Photographs and videos may be taken during the conference. Anyone attending the conference consents to such photography and filming without compensation and confirms that the Organizers shall be entitled to use such photographs and videos, which may include photographs and videos of visitors, for the purpose of marketing the conference in the future and for exploitation in any and all media, without liability.

Payment methods

Wire transfer, Credit card

Currencies accepted by this event

Swiss francs (CHF) ,  Euros (EUR) and US dollars (USD)

Instructions for Authors

Instructions
MMCS2024 will accept abstracts only. The accepted abstracts will be available online on Sciforum.net during and after the conference. Moreover, participants will have the opportunity to contribute a full manuscript to a Special Issue related to the conference in the open-access journal Molecules.
The conference will be held fully in person; it is not possible to participate online. Please note that abstract submission and conference registration are two separate processes. Please use your institutional email address for both processes.
To present your research at the event
  • Create an account on Sciforum if you do not have one and then click on ‘New Submission’ in the upper-right corner of the window; or, click on ‘Submit Abstract’ at the top of this webpage.
  • Choose a session that is best suited for your research.
  • Submit an abstract in English—the word limits are a minimum of 150 words and a maximum of 300 words.
  • The deadline to submit your abstract is 22 January 2024. You will be notified about its acceptance by 22 February 2024.
  • Upon submission, you can select if you wish to be considered for oral or poster presentation (or both). Following assessment by the Chairs and Scientific Committee, you will be notified by 22 February 2024 whether your contribution has been accepted for oral or poster presentation.
  • Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as the Covering Author, is required to cover the presentation and publication of any accepted abstract. The Covering Author registration deadline is 11 March 2024. Your abstract will be withdrawn if your registration is not complete by this date.
Oral Presentations

Invited talks will be 30 minutes long, including questions (25 minutes oral presentation + 5 minutes Q&A). Short talks will be 15 minutes long, including questions (10 minutes oral presentation + 5 minutes Q&A).

Please ensure that your slides are formatted in widescreen (16:9) aspect ratio.

Poster Presentations

Each presenter will be provided with a vertical poster board. Maximum poster size is limited to A0: 84 x 120 cm / 33 x 47 in (width x height) in the vertical orientation (portrait). Please print your poster prior to the conference. A plan for the poster session will be circulated later.

Publication Opportunities

Venue, Travel and Accommodation

Venue

Barcelona

Barcelona is the capital and largest city of Catalonia and is Spain's second-largest city, with a population of over one and a half million people.

Located on the northeastern Mediterranean coast of Spain, this city has a rich and diverse history, with its roots dating back to Roman times. The fruitful medieval period established Barcelona's position as the economic and political center of the Western Mediterranean. The city's Gothic Quarter bears witness to the splendor enjoyed by the city from the 13th to the 15th centuries.

The 20th century ushered in widespread urban renewal throughout Barcelona city, culminating in its landmark Eixample district, which showcases some of Barcelona's most distinctive Catalan art-nouveau, or modernista, buildings. The Catalan Antoni Gaudí, one of the most eminent architects, designed buildings such as La Pedrera, the Casa Batlló, and the Sagrada Família church, which have become world-famous landmarks.

In 1992, Barcelona gained international recognition by hosting the Olympic games, which brought about a massive upturn in its tourism industry. For visitors, this has translated into the very modern yet incredibly old city you see now in the 21st century, where new elements work to both preserve and celebrate the city’s heritage and origins.

Barcelona has plenty of outdoor markets, restaurants, shops, museums, and churches. The city is also very walkable, with an extensive and reliable Metro system for more far-flung destinations.

For a complete overview, see wikitravel.org or visit barcelonaturisme.com.

Foto de mediterraneo creado por bearfotos

2024 Sant Jordi Festival

The Sant Jordi Day is a unique celebration that takes place annually in Catalonia on April 23rd. Its origins lie in the legend of Saint George, the patron saint of Catalonia, who defeated a dragon to rescue a princess. Traditionally, on this day couples, friends and family exchange books and roses.

Barcelona transforms into an open-air bookshop, offering a wide selection of books spanning various genres. Roses, often adorned with symbolic touches such as the Catalan flag, become a treasured gift.

Sant Jordi Day not only honors culture and literature; but also creates a beautiful atmosphere on the streets. The air is filled with cultural activities, concerts, and events that revolve around the celebration of love and literature. Take this chance to immerse yourselves in the culture and customs unique to Catalonia!

The AXA Convention Center

The AXA Convention Centre is located in a vibrant modern zone of the city, with easy access from the airport, as well as the urban and suburban areas of the city. It is part of the "L'Illa Diagonal", a modern complex with a shopping center, two four-star hotels, several offices, a sports center, a public park, and a car park with 2500 spaces.


Address: Avinguda Diagonal, 547, 08029 Barcelona

Travel

By plane:

The international airport of Barcelona is called Barcelona-El Prat and is located 10 km from the city center. The airport is well connected to airport hubs in Europe and several locations around the world. For more information about the airport and flights, please visit the official website at https://www.aena.es.

Once you get to the airport, you have several options to reach the city center.

To the city center:

  • By shuttle bus: AEROBUS (https://aerobusbarcelona.es). This bus connects Barcelona Airport (Terminal 1 and Terminal 2) with the city center (Pl. Catalunya) in 35 minutes. It runs every day of the year with departures every 5 minutes and costs EUR 6,75.
  • By train: TRAIN R2 NORD (https://rodalies.gencat.cat). This train connects Terminal 2 of the airport with the city center (Barcelona–Passeig de Gràcia). It runs every day of the year with departures every 30 minutes and costs EUR 2,40.
  • By taxi: Taxis just outside the arrival area. The taxi from the airport to the city center (Plaza Catalunya) costs approximately EUR 30–35. Public taxis can apply four types of fares in Barcelona. These fares must be visible inside the taxi and are usually printed on a sticker over the window. Finally, the amount payable must be indicated on the taximeter. VTC apps that work in Barcelona are Bolt and Cabify and might offer cheaper rates.

To the conference venue:

  • By metro: LINE L9 (https://www.tmb.cat). This metro line connects Barcelona Airport (Terminal 1 and Terminal 2) with the northwest of the city (Zona Universitària). From here, you can take TRAM T1, T2, or T3 (get off at L'Illa stop) or bus 7 or 67 (get off at Diagonal—Entença stop) (https://www.tmb.cat). The metro from the airport costs EUR 5,15 and the tram or bus EUR 2,40. You can buy the bus/tram ticket at the tram stop or on the bus.
  • By taxi: Taxis just outside the arrival area. The taxi from the airport to the conference venue costs approximately EUR 30–35. VTC apps that work in Barcelona are Bolt and Cabify and might offer cheaper rates.

By train:

Barcelona Sants station is Barcelona's largest train station and provides rail services both in and around Barcelona and for the whole of Spain and beyond. For more information about the station and train service, please visit the official website at https://www.renfe.com.

Once you get to the station, you have the following options to reach the conference venue:

  • By bus: LINES V7 or 78 (https://www.tmb.cat).
  • By taxi: Taxis just outside the station. The taxi from the station to the conference venue costs about EUR 10.

Accommodation

We want your stay in Barcelona during the conference to be as comfortable as possible. With that in mind, we have agreed on a discount with several hotels to make your accommodation choice easier. Please book your accommodation online and contact the hotels directly with any issues or requests related to accommodation bookings.

We are delighted to announce that the following hotels will offer a discounted price for all MMCS2024 attendees:

  • Arenas Atiram: The Arenas Atiram Hotel offers a highly personalized service together with very friendly, elegant facilities, and it is within walking distance from the conference venue.
  • Oriente Atiram and Meson Castilla Atiram: Located in Las Ramblas, they have a fantastic central location next to Plaza Catalunya and the famous Boqueria market, 25–30 minutes away (by metro) from the conference venue.
  • Tres Torres Atiram: Located in the center of one of the best residential neighborhoods of Barcelona, next to the distinguished commercial and leisure districts, Diagonal Avenue, it is 1.5 km away from the conference venue.
Please add the 10% discount code ‘MDPI24’ while making your reservation in any of the Atiram hotels.
    • Hostal Aslyp 114: The Hostal Aslyp114 is a cozy hotel with private rooms located just 10 minutes away from the conference venue. Please add the 5% discount code ‘BCN114’ and indicate that you will be attending MMCS2024 while making your reservation.

    • The Social Hub Barcelona Poblenou: The Social Hub Barcelona is situated in the lively Poblenou district, and welcomes digital nomads, students, and travelers. Their unique community-focused concept merges a boutique hotel, student and extended stay rooms, a restaurant, a coworking space, bar, gym, terraces, solariums, and a Rooftop Bar & Pool with panoramic city views. Please add the 10% discount code ‘MDPI24’ while making your reservation.

    Beware of Unauthorized Registration and Hotel Solicitations

    Note that Sciforum is the only official registration platform to register to MMCS2024 and that we are not associated with any hotel agency (other than those listed above). While other hotel resellers and travel agencies may contact you with offers for your trip, they are not endorsed by or affiliated with MMCS2024 or Sciforum. Beware that entering into financial agreements with non-endorsed companies can have costly consequences.

    Visa Information

    Please note that you must apply for your own visa application. MDPI is not responsible for any visa application. However, MDPI can provide a Visa Support Letter. To be eligible for such a document, the criteria below must be fulfilled.

    Visa Support Letter

    • Applicants must have paid for registration and submitted an abstract in order to get a letter of support.
    • Applicants must provide us with a scan of their valid, in-date passport that contains a photo of them.
    • Applicants must provide us with an academic CV, two references from their institution (contact information including institutional email and phone), and a letter of support from their institution to confirm that they support the delegate attending the meeting.
    • This must be carried out in good time before the meeting; “last minute” requests will not be processed.
    More useful information on visa application

    Event Awards

    In order to recognize the works presented during the conference in the format of posters and presentations, two awards will be offered to our conference participants, sponsored by the journal Molecules. The Awardees will be announced during the Award Ceremony on the last day of the conference.

    The award winners will be selected by the Selection Committee after evaluation of all selected talks and posters presented at the conference.

    We will be offering the following two awards to our conference attendees:

    Best Oral Presentation

    Number of Awards Available: 1
    Prize: EUR 500

    Best Poster

    Number of Awards Available: 1
    Prize: EUR 300

    Sponsors and Partners

    We invite you and your company to participate in and sponsor MMCS2024! Find all information on sponsorship opportunities in our Sponsorship Agenda. If you have any questions or wish to discuss options further, please do not hesitate to contact the Conference Secretariat. We thank you for your consideration!

    Organizers


    Sponsors


    Partnering Societies


    Media Partners

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