30th Molecules Webinar

Multivalent Self-Assembled Systems for Biological Applications

Multivalency is a hallmark of biomolecular recognition, which applies to nucleic acids, proteins, and carbohydrates. The multivalent binding by synthetic nano-constructs is inspired by numerous biological systems such as viruses, and has strong potential in biological/biomedical applications, for instance, for the treatment of cancer or infectious diseases, as well as in targeted drug/gene/protein delivery and biosensing/bioimaging. Besides the rational or trial-and-error molecular engineering of multivalent systems, self-assembly approaches, using supramolecular or dynamic covalent chemistries, have emerged in the last two decades and attracted growing interest as a successful strategy for the identification of multivalent binders. Additionally, these multivalent self-assembled systems are dynamic and responsive, which enables the adaptation and the smart control of their self-assembly and disassembly by physico-chemical effectors. This webinar will showcase how self-assembly approaches can be implemented to provide the next generation of multivalent systems for biological applications.

Date: 31 January 2022

Time: 2:00pm CET | 8:00am EST | 9:00pm CST Asia

Webinar ID: 874 5499 6317

Webinar Secretariat: molecules.webinar@mdpi.com