Separations Webinar | (Young Scholars Workshop) Metric Tools for the Evaluation of Chromatographic Methods
the chair
5th Separations Webinar
(Young Scholars Workshop) Metric Tools for the Evaluation of Chromatographic Methods
In 1998, Paul Anastas and John Warner were the pioneers who coined the term “Green Chemistry”, as a result of high concern for human health and the protection of the environment from exposure to hazardous chemicals. Since then, many metric tools have been proposed to evaluate the green character of an analytical method. However, soon after, analytical chemists realised that greenness is not the only criterion to be taken into consideration when selecting an analytical method. The consideration of other parameters, such as the type of analysis, the number of compounds that can be determined in one run, the analytical technique and required instrumentation, the throughput, the commercial availability of reagents, the automation degree, the need for pre-concentration to meet legislation criteria, etc., is also essential. Therefore, the practicality and applicability of these approaches are also to be taken into account. Moreover, the analytical performance and innovation grade should, in the meantime, be evaluated using metric tools. The principles and the relevant indices will be described in the webinar, while the software and its application will be demonstrated.
Date: 4 December 2025
Time: 2:00 pm CET | 1:00 pm GMT | 9:00 pm CST Asia
Webinar ID: 879 2372 7206
Webinar Secretariat: journal.webinar@mdpi.com
Meet Our Speakers
Dr. Natalia Manousi
Institute of Chemical Technologies and Analytics, TU Wien, Vienna, Austria;
Natalia Manousi is a Post-Doctoral researcher at the Institute of Chemical Technologies and Analytics of TU WIEN, Vienna, Austria. She received her PhD in Chemistry from the Laboratory of Analytical Chemistry of the Department of Chemistry of Aristotle University of Thessaloniki in 2022. Her current research interests include the development of green and sustainable microextraction methodologies combined with chromatographic and spectrometric techniques. To date, she has published more than 100 research articles and is among the leaders of the task force Green metrics of the Sample Preparation Study Group and Network of the European Chemical Society–Division of Analytical Chemistry.
Dr. Adrián Fuente-Ballesteros
Analytical Chemistry Group (TESEA), I. U. CINQUIMA, Faculty of Sciences, University of Valladolid, Valladolid, Spain;
Adrián is a Postdoctoral Fellow in Analytical Chemistry at the University of Valladolid (Spain). His research focuses on the development and validation of novel analytical methodologies for the determination of target analytes in food and environmental matrices. He has worked extensively with bioactive compounds, alkaloids, plasticizers, and biogenic volatile organic compounds, with a background in the analysis of pesticide residues in bee products using chromatographic techniques (LC and GC-MS). Moreover, he specializes in integrating sustainability into analytical workflows through the design and application of assessment tools and metrics aligned with the principles of White Analytical Chemistry, aiming to promote greener and more practical methods. Throughout his career, he has established himself in the research community, having authored numerous publications, over 50 conference presentations, 2 book chapters, 1 patent, and delivering more than 30 science outreach activities, as well as having teaching experience and working on international collaborations. He is also an active reviewer and serves on the editorial boards of several high-impact journals. His contributions to the field have been recognized with several awards, including the IMFAHE Excellence Scholarship, the EuChemS Young Chemists’ Award, and the National Youth Science Award. He was also selected to join the Nova Talent Network, which brings together the top 3% of young talent.
Since 1998, when Paul Anastas and John Warner coined the term “Green Chemistry”, many metric tools have been proposed to evaluate the green character of an analytical method. However, soon after, analytical chemists realized that greenness is not the only criterion to be considered, when selecting an analytical method. The consideration of other parameters, such as practicality and applicability, should also be taken into account. Moreover, the analytical performance and innovation grade, should also be evaluated, using relevant metric tools. In the Separations Webinar | (Young Scholars Workshop) Metric Tools for the Evaluation of Chromatographic Methods, as a Part of the MDPI Separations Webinar series the key metrics and assessment tools that support method development, validation, and routine monitoring in chemical analysis were explored. The speakers, Dr Natalia Manousi and Dr Adrian de la Fuente Ballesteros, though young investigators, however experts in the field, will provide practical advice and details on a comprehensive understanding of how these metrics can be applied to enhance method reliability, and ultimately strengthen the quality of analytical results. The agenda included the presentation of 4 metric tools complementary to green metrics: Dr Natalia Manousi a post-doctoral researcher at the Institute of Chemical Technologies and Analytics of the Vienna University of Technology in Austria presented: 1) BAGI, Blue Applicability Grade Index 2) RAPI, Red Analytical Performance Index While Dr Adrian de la Fuente-Ballesteros a Post-doctoral Fellow in Analytical Chemistry at the University of Valladolid in Spain presented: 3) VIGI, Violet Innovation Grade Index 4) GLANCE: Graphical Tool for Analytical Chemistry method Evaluation The audience posed questions which were answered by the speakers. The take home message was that by integrating the presented metric tools into method development, analytical reliability is strengthened, while efficiency, traceability, and regulatory confidence are enhanced.
The webinar was hosted via Zoom and required registration to attend. The full recording can be found below. In order to learn about future webinars, you can sign up to our newsletter by clicking “Subscribe” at the top of the page.