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Biology Webinar | Non-alcohol and Non-infection-Associated Liver Diseases

13 December 2021
16:00 (CET)
Online

Welcome from
the chair

1st Biology Webinar

Non-alcohol and Non-infection-Associated Liver Diseases

Non-alcohol associated and non-infection liver injury is a liver disease of various etiologies which are not induced by chronic alcohol abuse or hepatotrophic viruses. Usually, this liver disease is associated with diabetes, dyslipidemia, bile acid metabolism dysfunctions and pro-inflammatory liver phenotype. These changes can be because of lifestyle (NAFLD/NASH), drug-induced, herb-induced and other metabolic abnormalities including those caused by genetic defects (Hemochromatosis, Wilson’s disease, Alpha-1 antitrypsin deficiency, Gilbert syndrome).

Date: 13 December 2021

Time: 4:00pm CET | 10:00am EST | 9:00am CST US | 11:00pm CST Asia

Webinar ID: 860 9093 1750

Webinar Secretariat: biology.webinar@mdpi.com



Meet Our Speakers

Prof. Dr. Kusum K. Kharbanda

Prof. Dr. Kusum K. Kharbanda

VA Nebraska-Western Iowa Health Care System, Department of Internal Medicine, University of Nebraska Medical Center, USA;
Dr. Kharbanda is a Professor at the University Nebraska Medical Center and the Omaha VA Medical Center. Her expertise is in understanding the role of alcohol-induced alterations in methionine metabolic pathways in the development and progression of liver injury. She is also examining the alterations in the methionine metabolic pathways in the gut and the adipose tissue and these changes in the gut-liver and the adipose-liver axes promotes more advanced liver injury. In addition, she is evaluating the efficacy of betaine and betaine analogs and esters in preventing and treating liver injury of various etiologies including alcohol and non-alcoholic steatohepatitis.

Sponsors and Partners

Organizer


MDPIBiology
Webinar Content

On Monday, 13 December 2021, MDPI and the Journal Biology organized the first webinar on Biology, entitled "Non-alcohol and Non-infection-Associated Liver Diseases".

The introduction was held by the Chair of the webinar, Prof. Dr. Kusum K. Kharbanda, Professor at the University Nebraska Medical Center and the Omaha VA Medical Center in the United States. Her expertise is in understanding the role of alcohol-induced alterations in methionine metabolic pathways in the development and progression of liver injury.

The first speaker to kick off this webinar was Prof. Dr. Valentina Medici. She is a Professor in the Division of Gastroenterology and Hepatology at the University of California Davis, United States. Her NIH-funded research focuses on the epigenetic regulation of gene expression in Wilson disease, a rare disease of hepatic and brain copper accumulation. Her presentation was entitled "The Epigenetic Regulation of Wilson Disease".

The second presentation with the title "Mechanisms of Acetaminophen Hepatotoxicity: From Animal Models to Human" was held by Prof. Dr. Hartmut Jaeschke. His major research interests include basic mechanisms and translational aspects of xenobiotic-induced hepatotoxicity and tissue repair with focus on acetaminophen overdose and mechanisms of inflammatory liver injury in animal models and humans. He is a University Distinguished Professor and Chairman of the Department of Pharmacology, Toxicology, and Therapeutics at the University of Kansas Medical Center, USA.

Prof. Dr. Natalie J. Torok from the Division of Gastroenterology and Hepatology at the Stanford University, CA, USA was the third speaker and her presentation was entitled "Aging and Nash". Her laboratory has been focusing on the mechanism of liver fibrosis and the role of hepatocyte cell death in fibrogenic injury.

The fourth and last presentation, entitled "A Selective PPARγ Modulator Reduces Hepatic Fibrosis" was held by Prof. Dr. Robert G. Bennett from the University of Nebraska Medical Center (USA). His research interests are in liver and adipose tissue fibrosis and the use of relaxin and PPARgamma agonists as anti-fibrotic agents.

The presentations were followed by a Q&A and a discussion, moderated by the Chair. The webinar was offered via Zoom and required registration to attend. The full recording can be found here on Sciforum website. In order to stay updated on the next webinars on Biology, be sure to sign up for our newsletter by clicking on "Subscribe" at the top of the page.

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Relevant SI
Non-Alcoholic Liver Injury
Guest Editors: Prof. Dr. Natalia Osna, Prof. Dr. Valentina Medici & Prof. Dr. Kusum K. Kharbanda
Deadline for manuscript submissions: closed (31 March 2021)

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