Program Overview
Detailed Program

Wednesday 29 March 2023

13:00 – 13.30

Registration Desk Open (Check-in)

13:30 – 13:45

Welcome from the Chairs

Session 1. Part I
Single Cell Multi-Omics Technologies and Analyses
Session Chairs: Peter Young

13:45 – 14:25

Keynote Talk: Manel Esteller - Using Single Cell Multiomics in Cancer: From Knowledge to Applications

14:25 – 14:40

Silvia Ogbeide - Single-cell multi-omics profiling in the study of colorectal cancer evolution

14:40 – 14:55

Francesca Nadalin - Single-cell multi-omic lineage tracing uncouples tumour initiation and drug tolerance in breast cancer

14:55 – 15:10

Enrico Sebastiani - An Investigation of the origin of neuroblastoma with single-cell transcriptomic analyses

15:10 – 15:25

Igor Filippov - Single-cell re-analysis of human transcriptomes reveals shared characteristics of immune ageing

15:25 – 15:50

Invited Talk:Anelia Horvath - Identification and analysis of cell-specific expressed genetic variants from scRNA-seq data

15:50 – 16:20

Coffee Break

Session 2. Part I
Artificial Intelligence in Single Cell Genomics
Session Chairs: Piotr Słowiński and Anelia Horvath

16:20 – 16:50

Invited Talk: Nacho Molina - Biophysics-informed interpretable deep learning to model gene regulation from single-cell and single-molecule genomic data

16:50 – 17:05

Kyoung Jae Won - Legible Gene Regulatory Network Reconstruction using Multivariate Transfer Entropy Over Single Cell Transcriptomics Data

17:05 – 17:20

Bogac Aybey - Immune cell type signature discovery and random forest classification for analysis of single cell gene expression datasets

17:20 – 18:00

Keynote Talk: Sandrine Dudoit - Learning from Data in Single-Cell Transcriptomics

20:00

Conference Dinner

Thursday 30 March 2023

Session 1. Part II
Single Cell Multi-Omics Technologies and Analyses
Session Chairs: Anelia Horvath and Irene Papatheodorou

08:30 – 09:00

Invited Talk: Merja Heinäniemi - Multimodal methods in single cell immunogenomics

09:00 – 09:15

Kalle Rytkönen - Gene regulatory network analysis of decidual stromal cells and natural killer cells

09:15 – 09:30

Alexandre Gaspar-Maia - Single cell multiomic analysis of Clonal Hematopoiesis reveals enhancer deregulation and increased COVID-19 inflammation severity

09:30 – 09:45

Sara Terzoli - Expansion of memory Vδ2 T cells following repeated exposure to mRNA SARS-CoV-2 vaccination

09:45 – 10:00

Alejandro Jiménez Sánchez - Optimized tumor metastatic phenotypes among distal metastatic lesions in pancreatic ductal adenocarcinoma

10:00 – 10:30

Invited Talk: Merav Cohen - The Functional Role of Immune-Related Intercellular Signaling Networks during Tissue Development and Cancer

10:30 – 11:00

Coffee Break sponsored by Parse Biosciences

Session 1. Part III
Single Cell Multi-Omics Technologies and Analyses
Session Chairs: Merav Cohen and Anelia Horvath

11:00 – 11:15

Enrico Gaffo - Benchmarking of methods for assessing circular RNA differential expression in single-cell RNA-seq data

11:15 – 11:30

Amy Hamilton - Unlocking the potential for single-cell sequencing at scale with combinatorial indexing

11:30 – 11:45

Celia Alda Catalinas - Mapping the functional impact of immune disease associated regulatory elements through single-cell CRISPR-based screens

11:45 – 12:00

Rapolas Zilionis - Robust and versatile ultra-high-throughput single-microbe genome sequencing

12:00 – 12:15

Veredas Coleto Alcudia - TOTEM: A Web Tool For Tissue Enrichment On Gene Lists With Single Cell Resolution

12:15 – 12:30

Emma Busarello - Harmonizing the annotation of single cells in normal and aberrant hematopoiesis with the Cell Marker Accordion

12:30 – 13:45

Lunch

Session 3
Spatial Genomics and Transcriptomics
Session Chairs: Merja Heinäniemi and Antonio Herrera Camacho

13:45 – 14:00

Kyoung Jae Won - Image processing approach to spatial genomics data identifies tissue architecture and cell-contact specific gene regulation

14:00 – 14:15

Biao Lu - Alteration of transcriptions loaded in engineered extracellular vesicles using transmembrane scaffolds

14:15 – 14:30

Susmita Datta - Inferring cell-cell communications from spatially resolved transcriptomics data

14:30 – 14:45

Alba Garrido Trigo - Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease

14:45 – 15:00

Kang Jin - Gene colocalization-aware segmentation of image-based spatial transcriptomics using Graph Neural Networks

15:00 – 15:30

Cofee Break

Session 1. Part IV
Single Cell Multi-Omics Technologies and Analyses
Session Chairs: Krasimira Tsaneva-Atanasova and Nacho Molina

15:30 – 16:00

Invited Talk: Björn Reinius - Dosage compensation dynamics unmasked by allele-specific single-cell transcriptomics

16:00 – 16:15

Evgenia Ulianova - Cell-Level Analysis of Telomeric Transcripts and Telomere-Associated Gene Variants

16:15 – 16:30

Meltem Omur - Characterization of gene regulatory networks and combinatorial transcription factor interactions during pancreatic β-cell differentiation

16:30 – 16:45

Florina Moldovan - Estrogen Regulation of POC5 centriolar protein by ERafla is Altered in Human Scoliotic Cells

16:45 – 17:00

Efthalia Preka - Dynamic transcriptomic alterations of microglia following cranial irradiation in the juvenile mouse hippocampus

17:00 - 17:30

Invited Talk: Antonio Herrera Camacho - Spatiotemporal transcriptomic mapping of the mouse embryonic brain under folate-deficient conditions

Friday 31 March 2023

Session 2. Part II
Artificial Intelligence in Single Cell Genomics
Session Chairs: Anelia Horvath and Nacho Molina

08:30 – 09:10

Keynote Talk:Oliver Stegle - From genotype to phenotype with single-cell resolution

09:10 – 09:25

Piotr Słowiński - Model-driven AI for multi-omics data analysis

09:25 – 09:40

Yunhee Jeong - scMaui: variational autoencoders combined with adversarial learning reveal cellular heterogeneity from single-cell multiomics data and handle multiple batch effects independently

09:40 – 10:10

Invited Talk: Krasimira Tsaneva Atanasova - Topological data analysis for single cell sequencing data

10:10 – 10:40

Coffee Break

Session 1. Part V
Single Cell Multi-Omics Technologies and Analyses
Session Chairs: Peter Young and Alexandre Gaspar-Maia

10:40 – 11:10

Invited Talk: Irene Papatheodorou - Computational analysis of cell atlases across species

11:10 – 11:20

Karin Engström - Comparison between scRNA-seq and snRNA-seq as sequencing strategies in five different tissues.

11:20 – 11:35

Martina Höckner - Single-cell analysis reveal Cd-related effects on immune cells (coelomocytes) from the earthworm Lumbricus terrestris

11:35 – 11:50

Ana Hernández de Sande - Cell-type-specific characterization of miRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease progression at single-cell resolution

11:50 – 12:05

Nadine Bestard Cuche - Marked regional heterogeneity of white matter glia in the human frontal lobe, cerebellum and spinal cord

12:05 – 12:20

Oksana Ivanova - LMNA R482L mutation-specific impairments of skeletal muscle metabolism are associated with pathological accumulation of reactive oxygen species

12:20 – 12:50

Invited Talk: Abel González -Somatic mutations in cancer and normal tissues

12:50

Award Ceremony and Closing Remarks


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