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Non-Coding RNA Webinar |Competitive Endogenous RNA Networks in Cancer

09 July 2025
16:00 (CEST)
Online

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Dr. Davide Barbagallo

Dr. Davide Barbagallo

Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy;
Davide Barbagallo is an Associate Professor of Experimental Biology at University of Catania, Italy (https://www.biometec.unict.it/docenti/davide.barbagallo?eng). Davide focused his research on non-coding RNAs since his PhD course, in 2005. In 2010, his PhD thesis was awarded as the best in the field of complex biological systems from the Gioenian Academy. In 2017 he was awarded the Umberto Veronesi Foundation Post-doctoral fellowship and he joined Professor Jørgen Kjems’ non-coding RNA lab, University of Aarhus, Denmark, where he spent 6 months to improve his knowledge on circular RNAs (circRNAs), another class of (mostly) non-coding RNAs, recently discovered as critical regulators of gene expression. During his stay at the non-coding RNA lab, under the tutorship of Dr. Thomas Birkballe Hansen, Davide cloned the sequence of circSMARCA5 into an expression vector and showed the tumor suppressive function and mechanism of action of this circRNA in glioblastoma multiforme. In 2018, Davide got back to University of Catania, at the Department of Biomedical and Biotechnological Sciences where he has continued his work on circRNAs. Davide published more than 60 articles, most of which centered on the study of non-coding RNAs and their involvement in the regulation of gene expression. The main application field of this knowledge is glioblastoma and, more recently, another brain tumor: meningioma. The study that will be described in this talk has been funded by the internal university funding of collaborative research PIACERI 2024-2026 / Linea di Intervento 1 - acronym of the project “MiPiaGli”.

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MDPINon-Coding RNA
Webinar Content

17th Webinar of Non-coding RNA

Competitive Endogenous RNA Networks in Cancer

In this webinar, Prof. Davide Barbagallo (Associate Professor at the Biomedical and Biotechnological Sciences Department, University of Catania, Italy) talks about the potential critical role exerted by circRNA-mediated competitive endogenous RNA (ceRNA) networks in Meningioma recurrence. In particular, Prof. Barbagallo describes the combined in silico and wet approach that led to the identification of a feed-forward gene expression loop mediated by a ceRNA network in recurring Meningiomas, paving the way for the study of this yet relatively unexplored field of research.

In this section, you will find the recordings of this webinar to watch, re-watch and share with your colleagues!


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