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Webinar on Clinical Medicine | New Developments about Portal Vein Thrombosis in Cirrhosis

Part of the Webinars on Clinical Medicine series
22 Mar 2022, 15:00 (CET)

Portal vein thrombosis, Cirrhosis, Pathophysiology, Management
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Welcome from the Chairs

6th Webinar on Clinical Medicine

New Developments about Portal Vein Thrombosis in Cirrhosis

Portal vein thrombosis (PVT) frequently affects patients with cirrhosis. However, while in the absence of cirrhosis PVT frequently relies on underlying pro-thrombotic factors (and consequently the need of anticoagulation is obvious), in the context of cirrhosis PVT is considered to be secondary to liver disease, and whether PVT is a cause or a consequence of impaired liver function is controversial.

In contrast with the formal suggestion to treat with anticoagulants PVT in the context of cirrhosis, the issue of the management of PVT remains controversial. Actually, in clinical practice, the decision in most of the cases is not to treat due to the fear for an increased bleeding risk. Additionally, accumulating evidence suggests that spontaneous recanalization of PVT may occur without treatment.

This webinar has the aim of exploring open issues regarding PVT in cirrhosis, in particular about pathophysiology, outcome and management.

Date: 22 March 2022

Time: 3:00pm CET | 10:00am EDT | 10:00pm CST Asia

Webinar ID: 832 5635 4366

Webinar Secretariat: jcm.webinar@mdpi.com

Chair

Medicina Interna 1, Azienda di Rilievo Nazionale ad Alta Specializzazione Civico - Di Cristina - Benfratelli, Palermo, Italy

Introduction
Bio
Physician and clinical researcher, mainly interested in the management of advanced liver diseases, vascular liver diseases, liver transplantation, HCC, liver diseases in thalassemia and iron overload, liver ultrasound. Actually, Consultant Medical Doctor at the Department of Internal Medicine, ARNAS Civico, Palermo, Italy. Since 2019, Referent the Regional Referral Centre for Rare Diseases, Budd-Chiari syndrome, hereditary hemorrhagic telangiectasia. Previously working as Consultant of Hepatology and Gastroenterology at the Ca’ Niguarda Hospital (Milan, Italy), of Gastroenterology and Endoscopy at V Cervello Hospital (Palermo, Italy), as well as in other hospitals all over Italy, and as clinical research fellow at the Liver Transplantation Unit and Hepatobiliary Medicine of the Royal Free Hospital, London, UK. Since 2017, alleged by the Italian Ministry of Education, University and Research to the National Scientific Qualification as Professor of Internal Medicine and of Gastroenterology and Hepatology. Author of much more the 100 English language published studies (first name in more than half). Peer-reviewer and Editor of plenty authoritative international Journals, mainly in the field of Hepatology, Gastroenterology, Internal Medicine, Hematology.

Invited Speakers

General Hospital of Northern Theater Command, Department of Gastroenterology, Shenyang, China

Introduction
Bio
Major research interests are vascular disorders of the liver (especially portal vein thrombosis and Budd-Chiari syndrome), liver cirrhosis, portal hypertension, and hepatocellular carcinoma. Major clinical skills include management of gastrointestinal, liver, biliary, and pancreatic diseases, and upper gastrointestinal endoscopy and colonoscopy. H-index (Scopus): 39. Total number of citations (Scopus): 5043.

Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, Groningen, the Netherlands

Introduction
Bio
Ton Lisman is a biochemist with a profound interest in translational clinical research. He received his PhD at the Department of Hematology from the University Medical Center Utrecht in The Netherlands on a thesis on the mechanism of action of recombinant coagulation factor VIIa in 2002. Since 2007, he works at the Surgical Research Laboratory and the Section of Hepatobiliary Surgery and Liver Transplantation at the Department of Surgery of the University of Groningen in The Netherlands. He was appointed full professor of Experimental Surgery in 2015. He serves as associate editor for the Journal of Thrombosis and Hemostasis and as senior associate editor for Seminars in Thrombosis and Hemostasis. His research interests include hemostasis in liver disease and liver surgery, the role of hemostatic components in damage and repair of liver tissue, and the role of the fibrinolytic system in thrombosis. These topics are studied in close collaboration with local and international clinical partners, which include surgeons, hepatologists, hematologists, intensivists, and anethesiologists.

Coordination of national referral centre for vascular disorders of the liver (CRMVF). Full time Hepatology and portal hypertension unit consultant, Hopital Beaujon, Clichy, France

Introduction
Bio
Woman and French hepatologist, consultant in the hepatology unit, Beaujon hospital, and in charge of the referral centre for vascular liver diseases. My research centres of interest are Vascular diseases of the liver, and portal hypertension. She has participated to European and coordinated national guidelines for vascular liver diseases. She is a member of Valdig steering committee, as a correspondent for ERN-rare liver, and also a member of ERN rare liver scientific committee, in charge of vascular liver diseases.

Webinar Content

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Program

Speaker/Presentation

Time in CET

Chair Dr. Andrea Mancuso

Controversies in the Management of Portal Vein Thrombosis in Cirrhosis

3:00 - 3:30 pm

Dr. Xingshun Qi

Evolution of Portal Vein Thrombosis in Cirrhosis

3:30 - 3:50 pm

Dr. Ton Lisman

Pathophysiology of Portal Vein Thrombosis in Cirrhosis: a Changing Scenario

3:50 - 4:10 pm

Dr. Aurelie Plessier

Prevention and Treatment of Portal Vein Thrombosis in Cirrhosis

4:10 - 4:30 pm

Q&A Session

4:30 - 5:00 pm

Closing of Webinar

Chair Dr. Andrea Mancuso

5:00 - 5:05 pm

Relevant SI

Portal Vein Thrombosis
Guest Editors: Prof. Dr. Andrea Mancuso, Dr. Giovanni Perricone, Dr. Xingshun Qi & Prof. Dr. Dominique Valla
Deadline for manuscript submissions: closed (10 December 2021)

Sponsors and Partners

Organizers

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