Estra-1,3,5(10),16-tetraene was converted to an estra-1\',3\',5\'(10\')- trieno(16\',17\':4,5)isoxazoline. The isoxazoline was transformed to a substituted 1- formylphenanthrene by the action of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ).

Platelet, tubular and herring-bone carbon nanofibres were doped with Pd under various conditions. The catalysts were analysed as to the Pd-content and as to the size distribution of the Pd particles. The Pd-doped carbon nanofibres were screened for their catalytic activity in the Suzuki-Miyaura cross coupling and in the Heck reaction.

The reaction of enantiopure 3-azido-4-oxoazetidine-2-carbaldehyde with acetone was catalyzed by L-proline, to give the corresponding aldol adduct. This product was stereocontrolled cyclized by using intramolecular reductive amination achieving a new 4-hydroxypipecolic acid analogue with a bicyclic b-lactam structure.

A commercial cordierite sample showed a small catalytic activity in iso-propanol conversion carried out at 150-350 °C and no measurable activity in CO oxidation by O2. On the other hand, supporting NiO on Al2O3–modified cordierite resulted in the formation of an active solid that having good catalytic activity in iso-propanol conversion and CO oxidation by O2. These two reactions were carried out at 150-350 and 200 °C, respectively. The results revealed that the catalyst containing 5wt (percent) NiO showed the biggest activity in the alcohol conversion and acted as selective dehydration catalyst. The catalyst sample containing 20wt (percent) NiO exhibited a good activity in CO oxidation by O2 which decreased progressively by increasing its calcination temperature within 350-600 °C. Al2O3–treated cordierite dissolved a portion of NiO in its lattice which increased by increasing the calcination temperature within 350-600 °C.

0.2CuO/MgO solids prepared by impregnation method was calcined at 350 and 450 ºC. The effects of γ-rays (0.2-1.6 MGy) on its structure, surface and catalytic properties were investigated by using XRD, N2–adsorption at -196ºC and catalytic conversion of iso-propanol at 150-275 ºC using a flow technique. The results revealed that the investigated solids consisted of nano-sized MgO as a major phase beside CuO and trace amount of Cu2O. γ- Irradiation of the solids investigated exerted measurable changes on their surface and catalytic properties. These changes are dependent on the calcination temperature and dose of irradiation. The catalysts investigated acted as active dehydrogenation solids. The five yearsageing of different solids showed a limited influence on surface and catalytic properties indicating a good catalytic stability of the prepared solids.

A series of novel bi-heterocyclic ethers, containing 4H-pyrido[1,2-a]pyrimidin-4-one along with other five and six-membered heterocyclic rings, was obtained utilizing ethyl [(4- oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)oxy]acetate (1), [(4-oxo-4H-pyrido[1,2-a]pyrimidin-2- yl)oxy]-acetic acid (2) and/or [(4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)oxy]acetohydrazide (3). Reaction of ester 1 with some ortho-hydroxy aldehydes furnished the corresponding pyridopyrimidyloxypyrones. Reaction of ester 1 or acid 2 with 1,2-diamines led to some imidazoles. Also, some pyrazole, triazole, and oxadiazoline derivatives have been prepared from hydrazide 3.

An efficient strereocontrolled synthesis of substituted oxazolidin-2-one synthon 11 as the key intermediate in the synthesis of FTY720 analogues starting from the highly functionalized furanose scaffold 21 is reported.

A series of N-substituted-3,4,5,6-tetrachlorophthalimides were prepared by a novel sequential reaction of trichloroacetimidate 3 with C-nucleophiles in the presence of TMSOTf. The nucleophiles include arenes, alkenes and active methylene to give the imidomethylation product of 3,4,5,6-tetrachlorophthalimide 5, 7, 9 and 11, respectively.

A combination of tetrachlorosilane (TCS) and phenol in dichloromethane was found to be an efficient reagent for hydrochlorination of α,β- unsaturated ketones to afford the corresponding β-chloroketones in good yield at ambient temperature.

We have developed a new catalytic asymmetric method for the synthesis of highly functionalized non-racemic chiral alkyl halides using Kharasch addition in good yields and moderate enantioselectivities.