The 16th International Electronic Conference on Synthetic Organic Chemistry

Part of the Electronic Conference on Synthetic Organic Chemistry series

Call for Papers

Name: The 16th International Electronic Conference on Synthetic Organic Chemistry
Start: 2012-10-31T23:00:00
End: 2012-11-29T23:00:00

The research concerned with synthetic organic chemistry is progressing fast and simultaneously, activities within both industry and academy are becoming more globalized. Successful research requires interaction with several units around the world. We are facing an obvious need for new and fast types of communication within our scientific community. Sciforum.net electronic conferences provide a platform for fast exchange of the latest research findings, as well as a possibility for global meetings with no limitations related to traveling.

The 16th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-16) will run from 1 - 30 November 2012. ECSOC-16 Proceedings will be published later online and as a CD-ROM edition. Posters presented at ECSOC-16 may be considered as preliminary communications of new research results or review papers and may be published in another form later in any standard journal. At the authors discretion, contributions will be removed from the web-site after the end of the conference and not included in the online and CD-ROM proceedings editions. Authors are invited to publish their papers subsequently in Molecules.

Conference Chairs

Julio A. Seijas

Universidad de Santiago de Compostela

Sessions

A. General Organic Synthesis
B. Bioorganic, Medicinal and Natural Products
C. Microwave Assisted Synthesis
D. Polymer and Supramolecular Chemistry
E. Computational Chemistry

Instructions for Authors

Procedure for Submission, Peer-Review, Revision and Acceptance of Conference Proceedings Papers

1. Scholars interested in participating with the conference can submit their abstract (about 200-300 words covering the areas of Communications for the proceedings issue) online on this website until 30 September 2012.

2. The conference committee will pre-evaluate, based on the submitted abstract, whether a contribution from the authors of the abstract will be welcome for this 16th edition of ECSOC. All authors will be notified by 10 October 2012 about the acceptance of their abstract.

3. If the abstract is accepted for this conference, the author is asked to submit his full communication paper, optionally along with a PowerPoint presentation of his/her paper, until the submission deadline of 20 October 2012.

4. The conference committee will then organize a round of peer-review of the submitted communication papers, and authors are eventually asked to revise their paper based on peer-reviewer's comments.

5. Finally, accepted communication papers will appear on the website immediately after their acceptance.

6. Presented communications papers can be discussed, commented and rated during the time of the conference, 1-30 November 2012.

Proceedings Paper

Communications for the proceedings issue must have the following organization:

Firstpage:

Title

Full author names

Affiliations and authors' e-mail addresses

Abstract

Keywords

Introduction

Methods / Experim

Results and Discussion

Conclusions

(Acknowledgements)

References

Communications should be prepared in MS Word or any other word processor and should be converted to the PDF format before submission. The publication format will be PDF. The Communication paper should count at least 3 pages (incl. figures, tables and references). There is no page limit on the length, although authors are asked to keep their papers as concise as possible.

Presentation Slides
Authors are encouraged to preare a couple of slides in PowerPoint or similar software, to be displayed online along with the Communication. Slides, if available, will be displayed directly in the website using Sciforum.net's proprietary slides viewer. Slides can be prepared in exactly the same way as for any traditional conference where research results can be presented. Slides should be converted to the PDF format before submission so that our process can easily and automatically convert them for online displaying.

Submission
Submissions should be done by the authors online by registering with www.sciforum.net, and using the "New Submission" function once logged into system.

Copyright
MDPI AG, the publisher of the Sciforum.net platform, is an open access publisher. We believe that authors should retain the copyright to their scholarly works. Hence, by submitting a Communication paper to this conference, you retain the copyright of your paper, but you grant MDPI AG the non-exclusive right to publish this paper online on the Sciforum.net platform. This means you can easily submit your paper to any scientific journal at a later stage and transfer the copyright to its publisher (if required by that publisher).

List of accepted submissions (110)

Id	Title	Authors	Poster PDF
sciforum-002721	The Influence of Maintenance Liquids\' Absorbence Used in the Automotive Industry on the Mechanical Properties of Polyamide-6/Montmorillonite Nanocomposites Tomasz Majka , Marcin Majka Submitted: 07 Sep 2012 Abstract: Show Abstract	Tomasz Majka , Marcin Majka	N/A	Show Abstract
In the present work, an upper limit of absorbance of demineralized water, antifreeze, windscreen washer fluid, brake fluid, gasoline and 15 wt% saline solution, on the polyamide-6 nanocomposites\' samples containing 3 wt% montmorillonite (PA-6 / MMT) was determined. The results were compared to the values obtained for pure nylon-6. The comparison allowed to evaluate the applicability of PA-6/MMT nanomaterials with potentially improved barrier properties for creating applications used in the automotive industry.
sciforum-002814	Synthesis of B-carboline Derivatives césar Bernardo , Ana Olival , António Ribeiro , Lígia Rodrigues , Ana Esteves , Ana Oliveira-Campos Submitted: 12 Sep 2012 Abstract: Show Abstract	césar Bernardo , Ana Olival , António Ribeiro , Lígia Rodrigues , Ana Esteves , Ana Oliveira-Campos	N/A	Show Abstract
b-Carboline (BC) alkaloids represent a number of natural and synthetic compounds, which are associated with a vast spectrum of pharmacological properties.¹ The Pictet-Spengler condensation is commonly used to synthesize tetrahydro-b-carbolines (THC). Some groups² describe a sequence of Pictet-Spengler condensation followed by oxidation, without the isolation of the intermediate THC, to prepare the BC. Using the above sequence several BC were obtained in medium yields. The synthesis started from tryptophan (Trp), tryptophan methyl ester (TrpMe), and 2-amino-3-(1H-indol-3-yl)-propionic acid prop-2-ynyl ester and used 3,4-dimethoxy benzaldehyde (Dmb), or ethanal, followed by oxidation with KMnO₄. From Trp, and Dmb the decarboxylated BC was obtained. From TrpMe and Dmb, the methyl ester of a BC was formed. A similar sequence with ethanal, gave an ester that was hydrolysed to theacid, which reacted with a glucosylamine under peptide conditions giving the amide, in low yield. From Boc-Trp the alkynyl derivative was prepared and the Pictet-Spengler reaction with ethanal gave the BC alkynyl ester. This was used for the click reaction³with an azide, produced in situ from treatment of a-acetobromoglucose with sodium azide. The final compound was obtained as an oil in good yield. Thanks to FCT, Portugal for financial support to the NMR portuguese network (PTNMR, Bruker Avance III 400-Univ. Minho) and to FCT and FEDER -COMPETE-QREN-EU for financial support to the Research Centre, CQ/UM [PEst-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716)] 1. R, Cao, et al, Curr Med Chem. 2007. 14, 479-500 2. B. Wu, et al, Eur. J. Med. Chem.. 2009. 44, 533-540 3. M. Silva, J. C.O. Gonçalves, A. M.F. Oliveira-Campos, L. M. Rodrigues, A. P. Esteves, Synth. Commun. DOI:10.1080/00397911.2011.637655
sciforum-000098	Epidermal Growth Factor Receptor (EGFR) Inhibitors for Tumor Anti-angiogenesis Activity Shriram Bairagi , Sachin Ladhha , Rajesh Lohiya , Jagdish Manwar Submitted: 14 Sep 2012 Abstract: Show Abstract	Shriram Bairagi , Sachin Ladhha , Rajesh Lohiya , Jagdish Manwar	N/A	Show Abstract
The EGFR family plays an essential role in normal organ development by mediating morphogenesis and differentiation through effects on cell proliferation, differentiation, apoptosis, invasion, and angiogenesis. Unlike normal cells that have tight regulatory mechanisms controlling EGFR pathways, tumor cells often have dysregulated EGFR signaling, allowing them to proliferate under adverse conditions, invade surrounding tissues, and increase angiogenesis. Epidermal growth factor receptor (EGFR) is a trans-membrane receptor tyrosine kinase that belongs to the Human epidermal receptor (HER) family of receptors. Receptor protein tyrosine kinases play a key role in signal transduction pathways that regulate cell division and differentiation. Among the growth factor receptor kinases that have been identified as being important in cancer is epidermal growth factor receptor (EGFR) kinase (also known as erb-B1 or HER-1) and the related human epidermal growth factor receptor HER-2 (also known as erbB-2). The quinazoline and other heterocyclic skeletonsare of great importance to chemists as well as biologists as it is available in a large variety of naturally occurring compounds. In this article we are emphasizing on various hetericycles such as Quinazoline, pyrrolotriazines etc. as promising anticancer agents. These hetocycles showed the anticancer activity through the inhibition of EGFR enzyme. Attempt will be taken to provide details information on the said topic in the benefit of medicinal chemist.
sciforum-000100	Multi-walled Carbon Nanotubes Functionalized with a Palladium(II)-Schiff Base Complex: A Recyclable and Heterogeneous Catalyst for the Copper-, Phosphorous- and Solvent-free Synthesis of Ynones Barahman Movassagh , Mozhgan Navidi , Saeed Rayati Submitted: 16 Sep 2012 Abstract: Show Abstract	Barahman Movassagh , Mozhgan Navidi , Saeed Rayati	N/A	Show Abstract
During the last decade, studies on the isolation, characterization and catalytic activity of functionalized carbon nanotubes (CNTs) received particular attention because of their specific catalytic applications compared to homogeneous catalysts. Schiff bases, which are an important class of ligands with extensive applications in different fields, showed excellent catalytic activity when grafted on CNTs.¹ Conjugated alkynyl ketones, best known as ynones, have received considerable synthetic interest due to their occurrence in a wide variety of bioactive molecules and natural products.² This class of compounds are synthesized through various reported methods.³ Some of the disadvantages of these protocols include high temperatures, long reaction times, use of air and moisture sensitive catalysts such as phosphorous containing catalysts, use of copper catalysts which are very much prone to form diyne side products, use of hazardous organic solvents, use of toxic carbon-monoxide gas and need of special instruments. In this work, we presented a solvent-, copper- and phosphorous-free cross-coupling reaction of terminal alkynes with acyl halides catalyzed by Pd-Schiff base@MWCNTs in the presence of triethylamine as base. The catalyst was reusable and air-stable which showed high activity for this simple, mild and green reaction with good to excellent yields of the product. References: [1] M. Salavati-Niasari, M. Bazarganipour, Appl. Surf. Sci. 2009, 255, 7610-7617. [2] C. A. Quesnelle, P. Gill, M. Dodier, D. St-Laurent, M. Serrano- Wu, A. Marinier, A. Martel, C. E. Mazzucco, T. M. Sticle, J. F. Barrett, D. M. Vyas, B. N. Balasubramanian, Bioorg. Med. Chem. Lett. 2003, 13, 519-524. [3] (a) Perrone, S.; Bona, F.; Troisi, L. Tetrahedron, 2011, 67, 7386; (b)Shen, Q.; Huang, W.; Wang, J.; Zhou, X. Organometallics,2008, 27, 301.
sciforum-000101	A Copper-, Phosphorous- and Solvent-free Coupling of Acyl Halides with Terminal Alkynes Catalyzed by Palladium-Cryptand-22 Complex under Aerobic Conditions Barahman Movassagh , Mozhgan Navidi Submitted: 17 Sep 2012 Abstract: Show Abstract	Barahman Movassagh , Mozhgan Navidi	N/A	Show Abstract
Ynones or α,β-acetylenic ketones are useful synthetic intermediates for the preparation of many biologically-active compounds and heterocyclic derivatives such as pyrroles, furanes, furanones, pyrazoles, and isoxazoles.¹ Different methodologies for the preparation of α,β-acetylenic ketones have been reported in which various metals have been employed as catalysts.² Unfortunately, there are several disadvantages that confine the utility of the given protocols. Namely, copper salts which are very much likely to form diynes have been used as a co-catalyst in many studies. Moreover, phosphorous containing ligands have made the reaction conditions harsher owing to the need of inert atmosphere such as argon and nitrogen. The use of hazardous organic solvents and high temperatures are also unfavorable. In this study, we have successfully demonstrated a solvent-, copper- and phosphorous-free cross-coupling reaction of terminal alkynes with acyl halides catalyzed by Pd-Cryptand-22 as catalyst. This catalyst was simply prepared and showed air and moisture stability. The reaction was performed at room temperature and under aerial conditions using triethylamine as base. The simple, mild and green procedure, short reaction times and moderate to excellent yields make this method well-suited for ynone synthesis. References: [1] (a) Zora, M.; Kivrak, A.; Yazici, C. J. Org. Chem. 2011, 76, 6726; (b) Karpov, A. S.;Merkul, E.; Oeser, T.;Muller, T. J. J. Eur. J. Org. Chem. 2006, 13, 2991. [2] Perrone, S.; Bona, F.; Troisi, L. Tetrahedron 2011, 67, 738.

Full List

List of Authors (189)

Hassan Abdallah

Francine AGBOSSOU NIEDERCORN

Francisco Aguirre-Crespo

Bassam al Hindawi

Nerea Alonso

Farah Barkhad

Rocío Barreiro

Jorgelina Barrios De Tomasi

Dariusz Bogdał

Bernhard Bugenhagen

Francisca Cabrera-Escribano

Amir Hossein Cheshmekhavar

Andrea Chicca

Elena Chigorina

Alicia Chopa

Marcella Corda

Sponsors and Partners

Media Partners

Proceedings & Editors

Editors

Julio A. Seijas

M. Pilar Vázquez Tato

Shu-Kun Lin

CD-ROM edition

ISBN: 3-906980-26-X

Published in 2013 by MDPI, Basel, Switzerland

Rates for CD-ROM archive edition

CHF 100 before the conference

CHF 150 after the conference

CHF 250 per year for non-participants and for institutions

Please place the order by e-mail: Billing

A. General Organic Synthesis

Covers papers dealing with different aspects of organic synthesis, where the synthesis of organic molecules is involved.

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B. Bioorganic, Medicinal and Natural Products

Covers papers where the molecules synthesized are of biological or medicinal interest, together with those which are natural products either they are isolated or synthesized.

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C. Microwave Assisted Synthesis

Covers papers dealing with the use of microwave irradiation for the enhancement of organic reactions.

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D. Polymer and Supramolecular Chemistry

In this section are collected papers related with different kinds of polymer including not only conventional but as well: dendrimers, molecular imprinted polymers, etc.

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E. Computational Chemistry

This section covers the aspects of computational chemistry related to the behavior and properties of organic molecules involved in synthetic processes.

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The 16th International Electronic Conference on Synthetic Organic Chemistry

Part of the Electronic Conference on Synthetic Organic Chemistry series

1–30 Nov 2012

Call for Papers

Conference Chairs

Sessions

Instructions for Authors

List of accepted submissions (110)

List of Authors (189)

Sponsors and Partners

Media Partners

Proceedings & Editors

A. General Organic Synthesis

Submissions

B. Bioorganic, Medicinal and Natural Products

Submissions

C. Microwave Assisted Synthesis

Submissions

D. Polymer and Supramolecular Chemistry

Submissions

E. Computational Chemistry

Submissions