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Optimization of Urea Formation with Phoxime™ Resin using the Nautilus™ 2400
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Published:
01 September 1997
by MDPI
in The 1st International Electronic Conference on Synthetic Organic Chemistry
session Combinatorial Synthesis and Automation
Abstract: Phosgenated p-nitrophenyl(polystyrene)ketoxime (Phoxime™) resin (1) has been previously utilized as a latent isocyanate equivalent. The Nautilus™ 2400 automated organic synthesizer was used to determine the optimal temperature for thermolysis of the polymer-bound oxime-carbamate derived from Phoxime resin and subsequent amine addition to give a urea in solution.
Keywords: n/a
