Solvent-Free Microwaves Assisted Amination of Haloarenes by Aromatic Nucleophilic Substitution

Alain PETIT; Giang VO-THANH

doi:10.3390/ecsoc-15-00763

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ISATIN PER-O-GLUCOPYRANOSYL THIOSEMICARBAZONES

Solvent-Free Microwaves Assisted Amination of Haloarenes by Aromatic Nucleophilic Substitution

Alain PETIT

Giang VO-THANH

¹ University Paris-Sud

Published: 31 October 2011 by MDPI in The 15th International Electronic Conference on Synthetic Organic Chemistry session Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-15-00763

Abstract: A rapid and efficient procedure for the synthesis of N-arylamines by aromatic nucleophilic substitution of activated as well as unactivated aryl halides with various amines using solvent-free microwaves activation under green chemistry conditions was described. Good to excellent yields were obtained in very short reaction time.

Keywords: solvent-free synthesis, microwave activation, aromatic nucleophilic substitution, amination.

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Alain PETIT

Giang VO-THANH