"Harvest Flight Synapse (HFS)" refers to the way in which a pollinator communicates and interconnects the organization of a flower system through a sequence of flight performed through the space of the vegetative architecture of a plant. It was identified HFS of Apis mellifera performed in a territory of the desert of Sonora, Mexico by visual monitoring of Stenocereus thurberi cacti individuals, located around the periphery of a cultivation area of Medicago sativa during flowering´s season. The importance of the HFS is that the pollinators establish a pre-designed flight transit order on the vegetative architecture so that subsequent visitors perform a flight sequence in which they include more floral structures, ensure pollination - harvest and at the same time stimulate the flowering. HFS prevailed initially from the east and the differences in time of stay in each column were not governed by their height or distance between them but by the number of columns with the presence of floral appendixes determined by their respective floral range and flowering scale. Communication and interconnection coexist in the bee-cactus relationship and allow sequencing the ecological processes in both organisms from the HFS.