Efficient Multi-component synthesis of new quinolines derivatives

¹ Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie Université d’Ain Témouchent, Faculté des Sciences et de la technologie, BP 284, 46000 Ain Témouchent, Algérie
² Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie Université d’Oran 1, Faculté de Médecine, B.P.1510, 31000 ELMENAOUAR Oran, Algérie
³ Departamento de QuímicaOrgánica, Facultad de Ciencias, Universidad de Santiago de Compostela, A da, Alfonso X El Sabio s/n, 27002 Lugo, Spain
⁴ Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie

Academic Editor: Julio A. Seijas

Published: 18 November 2022 by MDPI in The 26th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-26-13701 (registering DOI)

Abstract:

Nitrogen heterocycles represent a large class of organic molecules widely distributed in nature, which makes them of very great importance in scientific research because of their applications in various fields. Quinoline scaffolds are an important class of nitrogen heterocyclic compounds with a wide range of biological and therapeutic activities. The syntheses of quinolines derivatives have attracted considerable attention from organic researchers

We present, in this work, the synthesis of quinoline derivative using a new multi-component reaction to access to these structures in a simple, fast and efficient way.

Keywords: heterocycles, quinolines derivatives, multi-component reaction

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