One-Pot Synthesis of New imidazole derivatives

¹ Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie Université d’Ain Témouchent, Faculté des Sciences et de la technologie, BP 284, 46000 Ain Témouchent, Algérie
² Université d’Oran 1, Faculté de Médecine, B.P.1510, 31000 ELMENAOUAR Oran, Algérie
³ Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie Université d’Ain Témouchent, Faculté des Sciences et de la technologie, BP 284, 46000 Ain Témouchent, Algérie
⁴ Universidad de Santiago de Compostela, A da, Alfonso X El Sabio s/n, 27002 Lugo, Spain
⁵ Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie

Academic Editor: Julio A. Seijas

Published: 18 November 2022 by MDPI in The 26th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-26-13702 (registering DOI)

Abstract:

Imidazoles are one of the important classes of heterocyclic compounds because of their wide utility. These molecules are amphoteric which can react in both as an acid or as a base. Imidazole derivatives exhibit a wide range of biological and pharmacological activities including anti-fungal, anti-bacterial, anti-depressant, anti-cancer, and anti-viral. Due to their characteristic properties, many methodologies have been developed for constructing imidazole rings.

In this work,we present the synthesis of new Imidazole derivatives via a One-Pot reaction and using eco-friendly conditions.

Keywords: Imidazole, Heterocyclic, , eco-friendly conditions, One-Pot reaction.

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Braham Choukchou