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Synthesis, characterization and self aggregation of a new neo-pentylamide cholic derivative (Na-n-penC)
Victor Hugo Soto Tellini
1 ,
Francisco Meijide
1 ,
Aida Jover
1 ,
Luciano Galantini
2 ,
Juan V. Trillo Novo
1 ,
José Vázquez Tato
* 1
1  Universidad de Santiago de Compostela, Facultad de Ciencias, Avda. Alfonso X El Sabio s/n, 27002 Lugo, Spain
2  Dipartimento di Chimica and Research Center SOFT-INFM-CNR, Università di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy
Published: 30 November 2006 by MDPI in The 10th International Electronic Conference on Synthetic Organic Chemistry session Supramolecular Chemistry
https://doi.org/10.3390/ecsoc-10-01446
Abstract: The self-aggregation in aqueous solution of a new neo-pentyl amide of the 3-β-amino derivative of cholic acid (Na-n-penC) has been investigated in aqueous solution by surface tension and steady state-fluorescence spectroscopy of pyrene (used as a probe). The nature of the agregates was determined by transmission electron microscopy (TEM) revealing that vesicles are formed. The structure of the compound in the solid state was resolved by X-ray spectroscopy. The synthesis of the compound is also given.
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