Per- and polyfluoroalkyl substances (PFAS) is currently becoming a concern for the adverse health effects in mammals for health scientists and environmental technocrats. PFAS can be found in various type of waters like groundwater, drinking water, surface water, wastewater and in soil and dust from the household. The sources of PFAS can be various that includes but not limited to cleaning products, water resistant fabrics, cookware, personal care products and others. This PFAS contaminated soil and water can get into the bodies of animals and humans and cause various and chronic diseases which can be life threatening at times. There have been various methods of treating this PFAS from water -most of these methods rely on heavy chemical treatments and/or expensive filtration methods. In this review we tried to investigate the possibility for using bioremediation of PFAS by bacteria. Different microbial species have the ability of biodegrade or bio sequester different chemicals from the environment which otherwise be harmful to living species. Different bacterial species including Desulfovibrio aminophilus and Sporomusa sphaeroides that have been isolated from the nature have proven strong enough to cut the PFAS’ chlorine-carbon bond. In turn, that starts a chain of reactions that destroy the structures, rendering PFAS compounds harmless. Some fungal species have also shown enough evidence of degrading the PFAS. Some drawbacks of these research include the lack of data for long term studies. Most of the microbial species that have been used for treating PFAS show slow results for the process. Future aspects of these studies can be expanded for coupling various microorganisms together through batch reactor studies, aiming for a viable biological based solution for treating PFAS from urban water.