Introduction: Gestational toxoplasmosis (GT) results from Toxoplasma gondii infection during pregnancy, potentially causing severe fetal complications. Studying GT in Brazil is crucial to understanding clinical outcomes and gaps in epidemiological records.

Methods: A descriptive analysis of GT cases recorded in DATASUS from 2019 to 2024 was conducted. Data were extracted from the notification module in SINAN. Cases were classified into four outcomes: blank, cure, death due to GT, and death from other causes.

Results: The data showed 58,912 reported cases. Of these, 36,182 (61.4%) recovered, while 22,654 (38.4%) had unknown outcomes. Deaths totaled 76, with 39 attributed to GT and 37 to other causes.

Annual analysis revealed the highest notifications in 2022 (12,447 cases, 24.6%), followed by 2021 (11,093 cases, 22%) and 2023 (10,849 cases, 21.5%). The lowest numbers were in 2019 (8,436 cases, 14.3%) and 2024 (6,961 cases, 13.8%). Comparing pre-pandemic (2019) and post-pandemic years (2020-2024), the average number of reported cases remained stable, suggesting little impact from the pandemic.

Conclusions: GT remains a significant concern in Brazil, with 58,912 cases between 2019 and 2024. Most cases (61.4%) recovered, but 38.4% had unknown outcomes, reflecting gaps in reporting. The 76 deaths, including 39 from GT, highlight its severity. The 2022 peak may reflect improved surveillance or outbreaks, while the 2024 decline suggests control or underreporting. The stable case average pre- and post pandemic suggests minimal pandemic impact. However, limitations include unexamined confounders and high missing data rates, which may affect accuracy. Strengthening reporting, monitoring pregnant women, and investing in prevention are key to reducing GT's impact.