Synthesis of new water-soluble Bunte salts bearing thieno[2,3-b]pyridine-3-yl substituents

¹ Kuban State University
² Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya Str., 350040 Krasnodar, Russia
³ ChemEx Lab, Vladimir Dal’ Lugansk National University
⁴ North Caucasus Federal University

Published: 14 November 2020 by MDPI in The 24th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-24-08397

Abstract:

Upon treatment with chloroacetyl chloride, 3-aminothieno[2,3-b]pyridines gave the corresponding chloroacetamides. The latter readily react with sodium thiosulphate to afford water soluble S-alkylthiosulphates with pharmacophoric heterocyclic units.

Keywords: thieno[2,3-b]pyridines, Bunte salts, Thorpe-Ziegler reaction, heterocyclization

View paper

93 Reads