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Synthesis of new water-soluble Bunte salts bearing thieno[2,3-b]pyridine-3-yl substituents
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Published:
14 November 2020
by MDPI
in The 24th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
Upon treatment with chloroacetyl chloride, 3-aminothieno[2,3-b]pyridines gave the corresponding chloroacetamides. The latter readily react with sodium thiosulphate to afford water soluble S-alkylthiosulphates with pharmacophoric heterocyclic units.
Keywords: thieno[2,3-b]pyridines, Bunte salts, Thorpe-Ziegler reaction, heterocyclization
