21st Webinar on Cells
Airway Smooth Muscle and Asthma
This webinar is focused on airway smooth muscle biology and asthma pathogenesis, which is associated with the Special Issue ‘Airway Smooth Muscle and Asthma’. For this Special Issue, we invite authors to submit their original research articles and/or reviews reporting new developments in airway smooth muscle biology and asthma pathogenesis. Airway smooth muscle plays a multifaceted role in the physiological functions of the lung. Airway smooth muscle contracts and shortens in response to a wide range of endogenous and exogenous signals and, hence, represents the pivotal cell regulating bronchomotor tone, airway caliber, and ventilation distribution. Abnormal airway smooth muscle contraction is a key pathological process that induces airway hyperresponsiveness in asthma. Hence, inducing airway smooth muscle relaxation and inhibiting airway smooth muscle hyperreactivity are key strategies in controlling asthma attacks. Speaker 1, Dr. Penn, will provide us with the updated research on Biasing GPCR signaling in the airway as a therapeutic approach.
Although we know that airway smooth muscle plays an important role in regulating lung functions, there are many unanswered questions in this field. Speaker 2, Dr. Chun Seow, will give us updated research on the role of airway smooth muscle in regulating lung function.
Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations) and distinctive endotypes (mechanisms). It has been long thought that airway inflammation, particularly Th2 inflammation, is a driver of asthma pathogenesis. However, there is accumulating evidence to demonstrate that an inflammation-independent process also contributes to asthma pathogenesis. Speaker 3, Dr. Dale Tang, will provide us with the updated research on new developments of asthma pathogenesis, particularly focused on emerging mechanisms of asthma.
Date: 11 November 2022
Time: 3:00 pm CET | 6:00 am PST | 9:00 am EST | 10:00 pm CST Asia
Webinar ID: 881 0746 1503
Webinar Secretariat: cells.webinar@mdpi.com