We are pleased to announce the 4th International Online Conference on Vaccines (IOCV 2027), which will be held online and promoted by the open access MDPI journal Vaccines (ISSN 2076-393X, IF 3.4).

Vaccines remain one of the most powerful tools in modern medicine, and we stand at a uniquely transformative moment in their development. Cutting-edge technologies, including mRNA platforms, structure-based antigen design, single-cell sequencing, and artificial intelligence-driven immunogen optimization, are reshaping how we conceive, design, and evaluate vaccines. These advances are not only accelerating responses to emerging threats but also unlocking progress against some of the most persistent challenges in global health, including HIV and malaria. After decades of setbacks, next-generation HIV vaccine strategies leveraging broadly neutralizing antibodies and novel immunogen scaffolds are showing renewed promise, while landmark approvals of malaria vaccines mark a critical step forward that must now be matched by concerted efforts for ensuring global implementation and equitable access. IOCV 2027 brings together researchers, clinicians, and public health practitioners to address these scientific frontiers alongside the practical realities of vaccine deployment, uptake, and impact in diverse populations.

The IOCV 2027 invites researchers from academia, as well as vaccine practitioners, to contribute original findings, novel ideas, scientific concepts, and technological advancements related to the following:

• Advances in Vaccine Platforms and Delivery Systems;
• Innate Immunity, Trained Immunity, and Vaccine Responses;
• Adjuvants and Immune Modulators in Modern Vaccines;
• Vaccines for Chronic and Difficult-to-Control Infections, Including HIV and Malaria;
• Correlates of Protection and Systems Vaccinology;
• Emerging Pathogens and Pandemic Preparedness;
• Vaccine Implementation, Global Access, and Deployment Strategies.

As a fully online conference, IOCV 2027 provides a unique opportunity for researchers worldwide to participate without travel constraints, facilitating the real-time exchange of the latest findings and innovative ideas.

Your contributions and engagement are vital to the success of this 4th edition of the IOCV. Together, we have an opportunity to drive progress in overcoming the most pressing challenges in vaccine science today, ranging from conquering HIV and malaria to ensuring that life-saving vaccines reach every corner of the world. We look forward to your participation in shaping the future of vaccine research!

Kind regards,
Prof. Dr. Michael Bukrinsky
The George Washington University, Washington DC, USA

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Sessions

IOCV 2027 will accept abstracts only. The accepted abstracts will be available online on Sciforum.net during and after the conference.

Important Deadline
- Deadline for abstract submission: 08 November 2026.
- Abstract acceptance notification: 08 December 2026.

Please note:
An abstract acceptance email only confirms that your abstract has been accepted. Oral or poster presentation invitations are determined separately by the conference chairs, and you will receive an additional email with the presentation result.

1. Each abstract must designate one presenter. To change the presenter, please contact us after you receive the oral/poster presentation invitation.
2. Only live presentations are accepted.
3. Presenters who do not attend the live session will not be eligible for awards or presentation certificates.

The slot for the oral presentation is 15 mins. We advise that your presentation lasts for a maximum of 12 mins, leaving at least 3 mins for the Q&A session.

Authors are encouraged to prepare presentations using PowerPoint or equivalent software for online display alongside their abstract. If provided, slides will be presented directly on the conference website via the Sciforum.net slide viewer and should be prepared in the same format as a traditional conference presentation of research results. All slides must be converted to PDF format prior to submission to ensure accurate online display.

Each presentation should:
- Communicate the research question or objective, methodology, key results, and scientific novelty;
- Use a clear and logical structure, typically Introduction-Methods-Results&Discussion structure (IMRaD) or a field-appropriate alternative;
- Emphasize the relevance of the work;
- Support key findings with clear figures or tables where appropriate;
- Conclude with a critical interpretation of the results and their impact.

It is the author's responsibility to identify and declare any personal circumstances or interests that may be perceived as inappropriately influencing the representation or interpretation of clinical research. If there is no conflict, please state "The authors declare no conflicts of interest." This should be conveyed in a separate "Conflict of Interest" statement preceding the "Acknowledgments" and "References" sections at the end of the manuscript. Any financial support for the study must be fully disclosed in the "Acknowledgments" section.

MDPI, the publisher of the Sciforum.net platform, is an open access publisher. We believe authors should retain the copyright to their scholarly works. Hence, by submitting an abstract to this conference, you retain the copyright to the work, but you grant MDPI the non-exclusive right to publish this abstract online on the Sciforum.net platform. This means you can easily submit your full paper (with the abstract) to any scientific journal at a later stage and transfer the copyright to its publisher if required.

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