
Dear Colleagues,
It is with great pleasure that we announce the conference Viruses 2020 - Novel Concepts in Virology to be held in Barcelona, Spain, 5-7 February 2020.
Because of their global impact on human, animal, and plant health and their utility as tractable model systems, viruses continue to play a central role in all aspects of biomedical research, ranging from molecular and cell biology, structural biology, and immunology to evolution, epidemiology, and bioinformatics. This conference will bring together leading virologists from around the world and across the broad field of virology to share results of their recent studies. Meeting participants will have the opportunity to present posters and short talks on their work and discuss their research in a stimulating and collegial environment.
The conference is sponsored by MDPI, the publisher of the open-access journal Viruses and follows the very successful meetings Viruses 2016 - At the Forefront of Virus-Host Interactions held in January 2016 in Basel, Switzerland and Viruses 2018 - Breakthroughs in Viral Replication, held in February 2018 in Barcelona.
We very much look forward to seeing you at this exciting meeting in Barcelona.



















The detailed conference program of Viruses 2020 - Novel Concepts in Virology is available below. Moreover, you can download the online version of the Conference Proceedings Book inluding all abstracts, and the complete list of posters for both sessions at the following links (last update 4 February 2020):
Viruses 2020 Conference Proceedings Book
Poster Session A (Thursday 6 February 2020)
List of posters 1-73
Poster Session B (Friday 7 February 2020)
List of posters 74-147
Wednesday 5 February 2020: 09:00 - 13:00 / 14:00 - 18:30
Thursday 6 February 2020: 09:00 - 13:00 / 14:00 - 19:00 /Conference Dinner: 20:30
Friday 7 February 2020: 09:00 – 12:30 / 13:30 - 18:00
08:00–09:00 Check-In
09:00–09:15 Opening Ceremony (Eric Freed and Albert Bosch)
Session 1. General Topics in Virology (Part 1)
Chair: Shan-Lu Liu
09:15–10:00 Peter Palese (Keynote Opening Lecture): The Long Road to a Universal Influenza Virus Vaccine
10:00–10:30 Jason McLellan (Viruses Young Investigator Award Winner 2019): Structure of the RSV Polymerase Complex Reveals a Tentacular Arrangement of the Viral Phosphoprotein
10:30–10:45 Ariane C. Gomes: HCMV gB-MF59 vaccine primes the immune system of seronegative individuals to mount greater immunological responses upon challenge with virus at the time of solid organ transplant
10:45–11:00 Ritu Gaur: Insights into the activity of second-generation maturation inhibitors against HIV clade C
11:00–11:30 Coffee Break
Session 1. General Topics in Virology (Part 2)
Chair: Peter Nagy
11:30–12:00 Graham Hatfull (Invited Speaker): Mycobacteriophages: Diversity, dynamics, and therapy
12:00–12:15 Cristina Howard-Varona: Unveiling infection strategies across diverse marine phage-host systems
12:15–12:30 Hugo Oliveira: Bacteriophage depolymerases: evolutionary insights and antivirulence strategies against bacterial pathogens
12:30–12:45 Tae-Jin Choi: Bacteriophage biocontrol of Acidovorax citrulli, the causal agent of bacterial fruit blotch
12:45–13:00 Victor Latorre: Valosin-containing protein (VCP/p97) is a potential antiviral target against Mononegavirales
13:00–14:00 Lunch
Session 1. General Topics in Virology (Part 3)
Chair: Anna Cliffe
14:00–14:30 Michelle Flenniken (Invited Speaker): Honey Bee Viruses, Colony Health, and Antiviral Defense
14:30–14:45 Ioly Kotta-Loizou: A mycovirus mediates the virulence of an insect-killing fungus against the malaria mosquito vector
14:45–15:00 Lotty Birnberg: Small RNAs virome characterization reveals arthropod-associated viruses in Anopheles atroparvus from the Ebro Delta, Spain
15:00–15:15 Maria Vittoria Salvati: The persistent infection of tick cells by Hazara orthonairovirus is mediated by virus-derived DNA forms
15:15–15:30 Candace Fox: Histone Deacetylase Inhibitors Enhance Cell Killing and Block Interferon-Beta Synthesis Elicited by Infection with an Oncolytic Parainfluenza Virus
15:30–16:00 Coffee Break
Session 2. Structural Virology Session
Chair: Polly Roy
16:00–16:30 Cristina Risco (Invited Speaker): Imaging Viral Factories
16:30–17:00 K. Andrew White (Invited Speaker): Regulation of RNA Virus Processes by Viral Genome Structure
17:00–17:15 Reidun Twarock: Viral genome conformations and contacts across different life-cycle stages
17:15–17:30 Jamil Saad: Structural basis for Env incorporation into HIV-1 particles
17:30–17:45 Ekaterina Heldwein: Structural basis for capsid recruitment and coat formation during HSV-1 nuclear egress
17:45–18:00 James Munro: Conformational dynamics related to membrane fusion observed in single Ebola GP molecules
18:00–18:45 Selected Posters Flash Presentations
Chair: Jamil Saad
- Alex Compton: The intrinsic link between metabolic and antiviral states of the cell (Poster No. 130)
- Ornela Chase: Deciphering the RNA Silencing Suppressor Function in the Potyvirus SPV2 (Poster No. 52)
- Matthias Götte: Independent Inhibition of the Polymerase and Deubiquitinase activities of the Crimean–Congo Hemorrhagic Fever Virus Full-Length L-protein (Poster No. 82)
- Jiri Hejnar: CRISPR/Cas9 Editing of Viral Receptors and Biotechnological Approach to Host Resistance (Poster No. 51)
- Shan-Lu Liu: Restriction of HIV by TIM and SERINC and Counteraction by Nef (Poster No. 14)
- Antonio Mas: Usutu Virus NS5: Characterization of Polymerase Activity, Protein-Protein Interaction and Cellular Localization (Poster No. 138)
- Craig McCormick: KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication (Poster No. 12)
- Delphine Muriaux: Specific lipid recruitment by the retroviral Gag protein upon HIV-1 assembly: from model membranes to infected cells (Poster No. 121)
- Jack Stapleton: Yellow Fever Virus Vaccine Reduces T Cell Receptor Signaling and the Levels of Phosphatase PTPRE In Vivo (Poster No. 143)
Session 3. Antiviral Innate Immunity (Part 1)
Chair: Gregory Melikian
09:00–09:30 Susan Weiss (Invited Speaker): Activation and antagonism of the OAS-RNase L pathway
09:30–09:45 Saguna Verma: Modeling of Zika virus infection and antiviral immunity in 2D and 3D in vitro systems of human testis
09:45–10:00 Linda Brunotte: Human IFN-alpha; subtypes display non-redundant antiviral activities against H3N2 influenza A virus in the human lung
10:00–10:15 Carlos Maluquer de Motes: Poxin/vSchlafen: a novel viral strategy to subvert cytosolic DNA sensing
10:15–10:30 Gregory Melikyan: Mechanism of inhibition of viral fusion by interferon-induced transmembrane proteins
10:30–11:00 Coffee Break
10:30 – 10:35 Conference Group Photograph
Session 3. Antiviral Innate Immunity (Part 2)
Chair: Susan Weiss
11:00–11:30 Stacy Horner (Invited Speaker): A role for the RNA modification m6A at the virus-host interface
11:30–11:45 Idoia Busnadiego: Non-canonical interferon-stimulated pathways in antiviral defense
11:45–12:00 Matthew Murray: Type I interferon activity promotes a cellular environment that supports the establishment of latency by human cytomegalovirus
12:00–12:15 Daniel Blanco-Melo: An inability to maintain the ribonucleoprotein genomic structure results in host detection of negative strand RNA viruses
12:15–12:30 Dong-Yan Jin: Interferon antagonism of Epstein-Barr virus tegument proteins
12:30–12:45 Kevin Groen: Induction of the type-I IFN response by Human Metanpneumovirus lacking SH, G or M2.2 expression
12:45–13:00 Daniela Ribeiro: Peroxisomes as platforms for cytomegalovirus’ evasion from the cellular antiviral signalling
13:00–15:00 Lunch
13:30–15:00 Poster Session A
Session 4. Viral Pathogenesis (Part 1)
Chair: Craig McCormick
15:00–15:30 Rotem Sorek (Invited Speaker): Beyond CRISPR: The immune system of bacteria
15:30–15:45 Sylvie Alonso: Relative contribution of non-structural protein 1 in dengue pathogenesis
15:45–16:00 Autumn LaPointe: Noncapped genomic RNA are critical for Alphaviral infection and pathogenicity
16:00–16:15 Ifeanyi Ezeonwumelu: SAMHD1 is a modulator of nucleos(t)ide analogue efficacy
16:15–16:30 Jonathan Kinder: Examining human metapneumovirus infection and spread in a human airway epithelial model
16:30–17:00 Coffee Break
Session 4. Viral Pathogenesis (Part 2)
Chair: Ioly Kotta-Loizou
17:00–17:30 Martin Beer (Invited Speaker): Lethal encephalitis of unknown origin - elucidation by metagenomics
17:30–17:45 Luca Zaeck: High-resolution 3D imaging of virus infections in solvent-cleared organs; novel insights into virus replication and tropism in vivo
17:45–18:00 Saveez Saffarian: Dynamics in HIV Gag lattice detected by time-lapse iPALM
18:00–18:15 Diego Sebastian Ferrero: From structure to mechanisms of Zika virus induced neurodevelopmental disease
18:15–18:30 Brett Lindenbach: A sensitive Yellow Fever Virus entry reporter identifies valosin-containing protein (VCP/p97) as an essential host factor for Flavivirus uncoating
18:30–18:45 Lingyan Wang: Analysis of Programmed Cell Death Induced by HCV Infection
18:45–19:00 Anna Cliffe: Reactivation of Herpes Simplex Virus (HSV) from Latency in Response to Neuronal Hyperexcitability
20:30 Conference Dinner
Special Session. New Coronavirus Outbreak
Chairs: Eric Freed and Albert Bosch
09:00–09:10 Susan Weiss: Human Coronaviruses as Emerging Pathogens
09:10–09:20 Christine Prat: Latest Virus Outbreaks: nCov2019 and Zika Virus, Preparedness is the Key. Lessons Learnt from the Perspective of the "European Virus Archive Global (EVAG)" EU Funded Research Infrastructure
09:20–09:30 Q&A/Discussion Round
Session 5. Mechanisms of Virus Replication (Part 1)
Chair: Jack Stapleton
09:30–10:00 Rosa Pintó (Invited Speaker): Hepatitis A virus replication stimulates the expression of genes coding for proteins involved in the syndecan-ALIX- mediated exosome biogenesis
10:00–10:15 Selena Sagan: A moonlighting microRNA: mechanism(s) of miR-122-mediated viral RNA accumulation
10:15–10:30 Alexander Rouvinski: Functional and structural characterization of novel insect restricted Negev viruses and their interaction with the host cells
10:30–11:00 Coffee Break
Session 5. Mechanisms of Virus Replication (Part 2)
Chair: Brett Lindenbach
11:00–11:30 Diane Griffin (Invited Speaker): Control of alphavirus replication in neurons
11:30–11:45 Oscar Burrone: Impact of capsid anchor length and sequential processing on the assembly and infectivity of Dengue virus
11:45–12:00 Thejaswi Nagaraju: 4D analyses show that replication compartments are clonal factories in which Epstein-Barr Viral DNA amplification is coordinated
12:00–12:15 Peter Nagy: Exploitation of host factors and cellular pathways by tombusviruses for the biogenesis of the viral replication organelles
12:15–12:30 John Patton: Rotaviruses as Neonatal Vaccine Expression Vectors against Other Enteric Pathogen
12:30–14:30 Lunch
13:00–14:30 Poster Session B
Session 6. Viral Genetics and Evolution (Part 1)
Chair: Alex Compton
14:30–15:00 Eric Freed (Invited Speaker): Mutations in the HIV-1 Envelope Glycoprotein Confer Broad, Multi-Class Drug Resistance
15:00-15:15 Miguel Muñoz-Alía: Defining Measles virus hemagglutinin antigenic drift by systematic B-cell epitope elimination
15:15-15:30 Nancy Beerens: Emergence and selection of a highly pathogenic avian influenza H7N3 virus
15:30–15:45 Matthew Evans: Deep mutational scanning to map how Zika envelope protein mutations affect viral growth and antibody escape
15:45–16:00 Ron Geller: Globally defining the effects of amino acid mutations across a picornavirus capsid
16:00–16:30 Coffee Break
Session 6. Viral Genetics and Evolution (Part 2)
Chair: Nathalie Arhel
16:30–17:00 Marco Vignuzzi (Invited Speaker): Good and bad neighbourhoods in viral sequence space: predicting, altering, targeting virus populations
17:00–17:15 Juan Vicente Bou: Coxsackieviruses undergo intercellular transmission as pools of sibling viral genomes associated to membranes
17:15–17:30 Joanna Kaczorowska: Revolution in evolution of human ”Anellome”
17:30–17:45 Pablo Martinez-Vicente: Divergent traits and ligand-binding features of the cytomegalovirus CD48 gene family
17:45–18:00 Closing Remarks and Awards Ceremony
Follow the conversation on Twitter with #Viruses2020
Thursday 6th February, 20:30
50€ per person

We invite you to join us at the Conference Dinner at La Camarga, a cutting-edge restaurant specialized in Mediterranean cuisine with deep gastronomic roots that inspires dishes full of contemporary flavours and textures.
This will be at an additional cost of 50€ and will need to be added to your booking when you register. Please note that the number of seats is limited: once the number of paid registrations reaches the maximum number of participants, unpaid registrations will be cancelled.
La Camarga is located at Carrer d'Aribau, 117, only a few minutes away from Passeig de Gràcia, one of the major avenues in Barcelona and one of its most important shopping and business areas, containing several of the city's most celebrated pieces of architecture (such as La Pedrera or Casa Batlló). You can easily reach the restaurant either by taxi, bus or Metro. If you were to choose the second option, the closest metro stations are "Hospital Clinic" on Line 5 (blue), "Diagonal" on Line 3 (green).