Synthesis of New 2-(3-Hydroxy-4-oxo-4Hnaphthalenylidene) acetonitriles in Aqueous Solvent

Didier Villemina; Mohammed Benabdallah; Nadjib Rahmounb; Noureddine Choukchou-Braham; Bachir Mostefa-Karab

doi:10.3390/ecsoc-12-01202

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Synthesis of New 2-(3-Hydroxy-4-oxo-4Hnaphthalenylidene) acetonitriles in Aqueous Solvent

Didier Villemina

^{*

1},

Mohammed Benabdallah

^{1, 2},

Nadjib Rahmounb

²,

Noureddine Choukchou-Braham

²,

Bachir Mostefa-Karab

¹ ENSICAEN, LCMT-UMR 6507 CNRS, Université de Caen, 14050 Caen, France
² Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université Abou-Bakr Belkaid, BP 119, 13000 Tlemcen, Algérie

Published: 28 November 2008 by MDPI in The 12th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-12-01202

Abstract: We have prepared a serie of new naphthoquinomethanes: [2-(3-hydroxy-4-oxo-4H-naphthalen-1-ylidene) acetonitriles] by the cascade Michael-elimination reaction of sodium 1, 2-naphthoquinone-4-sulfonate with substituted acetonitriles in basic ethanol-water.

Keywords: lawson, antibacterial, Michael addition, 3-hydroxy-1,2-naphthoquinomethane, green chemistry

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Didier Villemina

Mohammed Benabdallah

Nadjib Rahmounb

Noureddine Choukchou-Braham

Bachir Mostefa-Karab