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Formulation and Evaluation of Verdant Tablets Containing Saponin-coalesced Silver Nanoparticles Got From Fenugreek Seed Extract
* 1, 2 , * 3, 4 , 5, 6 , 7
1  Associate Professor, Dept. of Pharmacognosy & Phytochemistry, PSGVP Mandal’s College of Pharmacy, Shahada, Tal- Shahada, Dist- Nandurbar (M.S), 425409, India
2  Contact No. +919923441004
3  Assistant Professor, Dept. of Pharmacognosy & Phytochemistry, PSG Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Tal- Shahada, Dist- Nandurbar (M.S), 425409, India
4  Contact No. +919970737273
5  Assistant Professor, Dept. of Pharmacology, PSG Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Tal- Shahada, Dist- Nandurbar (M.S), 425409, India
6  Contact No. +918668641172
7  Dept. of Pharmacognosy & Phytochemistry, PSG Vidya Prasarak Mandal’s College of Pharmacy, Shahada, Tal- Shahada, Dist- Nandurbar (M.S), 425409, India
Academic Editor: Julio A. Seijas

Abstract:

Presently nanoparticles are in demand due to several applications. Commercially used Metallic nanoparticles are usually comprised of synthetic chemicals. These chemicals are noxious and combustible. Current research had the objective to explore the advantages of nanoparticles using herbal material, hence we developed silver nanoparticles of aqueous extract of Trigonella foenum-graecum (Fenugreek) seeds and formulated them into tablets. Fenugreek seeds contain steroidal sapogenins and are responsible for the reduction of blood cholesterol levels, control diabetes, enhance breast milk production, digestion aid, and helps in weight loss hence prepared formulation can be recommended in all the above cases. The pre-compression parameters evaluated for formulations are bulk density, tapped density, Carr’s index Hausner's ratio, angle of repose and results are 0.16gm/cc, 0.86gm/cc, 14.16, ratio 1.13 and 32° respectively; whereas post-compression parameters are weight variation, friability, hardness, thickness, and disintegration were evaluated the results are 0.504gm, 0.2%, 3.21gm/cm2, 2.55mm, and 07min respectively.

Keywords: Nanoparticles; Fenugreek; Steroidal sapogenins; Aqueous extract; Tablet; Evaluation
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