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Synthesis of tetrakis-tetrazole via a repetitive MCR
Published:
14 November 2020
by MDPI
in The 24th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
The synthesis of two novel and complex molecules tetrakis-tetrazole were synthesized via a Ugi-azide repetitive reaction from easily accessible starting materials in good yields. The use of orthogonal bifunctional reagents in isocyanide based multicomponent reactions (IMCR) allowed us the synthesis of structurally complex molecules in one pot manner. The molecules herein synthesized could have applications, such as chelating agents and organocatalysis.
Keywords: tetrakis-tetrazole; Ugi-azide; I-MCR, chelating agents.