Flame retardants (FRs) are widely used to reduce the flammability of commercial products. Amongst them, Tetrabromobisphenol A (TBBPA), a persistent chemical, is used extensively in textiles, plastics, electronics, and electrical equipment. TBBPA is frequently detected in aqueous (ranging from 0.14 to 130 ng L^-1) and biological samples (up to 1.15 μg L^-1 in urine samples). Studies on TBBPA and its degradation products' toxicity have shown their impact in both humans and animals, highlighting their cytotoxic, cardiotoxic, and immunotoxic effects. The conventional treatment processes have often presented limitations, and numerous organic pollutants are highly resistant to them. In recent decades, advanced oxidation processes (AOPs) have been harnessed to efficiently eliminate organic contaminants from water and wastewater.

Therefore, the aim of the present study was to effectively remove TBBPA and its characteristic degradation products using a low-cost and practical AOP combining a widely used oxidant and solar irradiation. High degradation percentages were achieved at the first stages of the treatment, with almost complete removal of TBBPA. The efficiency of the process was also evaluated using certified bioassays that are widely used for the estimation of toxic effects in various organisms of different trophic levels. Based on the results, the treated samples did not induce toxic potential, suggesting the efficiency of using AOPs to remove persistent organic pollutants from water.