Benzene‑1,3,5‑tricarboxylic acid‑functionalized Cherry gum as a novel and recoverable nanocatalyst for efficient synthesis of 1,4-polyhydroquinoline derivatives

Hossein Ghafuri; Behnaz Abbasi; Nastaran Ghanbari; Yegane Rostami; Zeinab Tajik

doi:10.3390/ecsoc-25-11717

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Benzene‑1,3,5‑tricarboxylic acid‑functionalized Cherry gum as a novel and recoverable nanocatalyst for efficient synthesis of 1,4-polyhydroquinoline derivatives

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¹ Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran16846-13114, Iran

Academic Editor: Julio A. Seijas

Published: 14 November 2021 by MDPI in The 25th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-25-11717

Abstract:

In this study, Benzene-1,3,5-tricarboxylic acid (BTA)-functionalized gum (Cherry gum) (gum-Pr-BTA), as a novel nanocatalyst was prepared. This novel nanocatalyst was used for the expeditious and efficient synthesis of 1,4-polyhydroquinoline derivatives, as an important pharmaceutical scaffold, in ethanol reflux conditions. This method has several advantages such as high yields, low catalyst loading, short reaction times, and simple workup and could be used up to five reaction cycles without a noticeable decrease in catalytic activity.

Keywords: Benzene-1,3,5-tricarboxylic acid (BTA), Cherry gum, nanocatalyst, ,4-polyhydroquinoline derivatives.

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