Synthesis and antibacterial activity of thymyl ethers

¹ Department of Chemistry, Uttamrao Patil Arts and Science College, Dahivel, Tal. Sakri, Dist.- Dhule. (Maharashtra) , India.
² Department of Applied Science and Humanities, R. C. Patel Institute of Technology, Shirpur 425405
³ Synthetic Organic Research Laboratory,Department of Chemistry Pratap College, Amalner,Dist. – Jalgaon 425 401

Academic Editor: Julio A. Seijas

Published: 14 November 2021 by MDPI in The 25th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-25-11747

Abstract:

We have reported herein a simple and efficient synthesis method of thymyl ethers for structural modifications of natural products such as monoterpenoids and studies of ether derivatives of thymol in biological importance.The investigations showed that thymol reacts very smoothly with different types of substituted acetanilides.The synthesized compounds have been tested for their bacterial potency against four bacterial species. Such a structural modification will be beneficial in the field of pest management for designing the active molecules.

Keywords: Thymol, Monoterpenoids, Green Chemistry, Microwave irradiation and Antibacterial activity

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