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Prediction in infection of Helicobacter Pylori with machine learning
1  Biology departament
Academic Editor: Humbert G. Díaz

Abstract:

Infection by the Helicobacter Pylori microorganism is one of the most common causes of infection, with half of the cases being almost undetectable due to being asymptomatic. This microorganism is responsible for the development of gastric cancer in addition to other metabolic disorders and changes. The problem lies in the fact that in addition to the existence of asymptomatic patients, the conventional methods that currently exist can give false negatives for H. Pylori infection, which can aggravate cases of gastric cancer or even death.
As a result, a different approach to the diagnosis of H. pylori infection has been sought with the artificial intelligence of machine learning and an attempt is made to find a prediction of infection by visual inspection of the gastric mucosa. However, there is no established method of optical diagnosis of H. pylori infection using endoscopic imaging. In this study the objective was to find and demonstrate a reliable precision in the detection by images in the detection of the microorganism.
For the use of information for the study, two independent evaluators carried out independent searches in the most important databases and inclusion data were used where the most notable were endoscopic images without H. pylori infection as a control group and others with images of endoscopy with H. Pylori infection as a group of cases. Disagreements between evaluators were resolved by consulting a third evaluator. Subsequently, a precision meta-analysis of the diagnostic test of 8 studies was performed using criteria such as pooled sensitivity, specificity, diagnostic odds ratio, and area under the AI curve for the detection of H. pylori infection. The use of the AI algorithm reached a total of 82% for the discrimination between infected images against uninfected images.
With this, it can be concluded that the use of algorithms with artificial intelligence as in a field of medicine in the detection of infection of pathogenic organisms is super effective, even being able to give reliable results more quickly.

Keywords: Helicobacter pylori; Machine learning;
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