Red radish (Raphanus sativus L.) is a worldwide consumed vegetable, which has particular interest, not only for its particular taste, but also for its health-promoting properties. Most of them come from the presence of anthocyanins, glucosinolates and flavonols, whose benefits have been widely reported. However, little is known about how abiotic stress could affect the presence of these biomolecules in an adult plant of red radish. In the Region of Murcia, Spain, one of the mayor issues concerning due to edaphoclimatic and economic factors is salinity stress. One of the main concerns of salinity stress is the reduction in plant size, provoking a diminishing in crop production. For all that, this work aims to analyse the effect of salinity in red radish physiology and metabolism. To this point, a study based on hydroponic culture was designed to evaluate the effects of salinity (0. 40. 80 and 120 mM) in plant size, discerning between the bulb and the aerial part. Furthermore, RP-HPLC-DAD analysis was performed in order to determine secondary metabolites of red radish. Preliminary results suggest that salinity stress at high concentrations compromises the plant vegetative development. However, stresses are widely reported to stimulate the secondary metabolism, hindering the processes of finding a balance between nutritional value and production.