This is a talk by Dr. Romero Duran from a series presented as part of the NEURODAT’21 training program funded by IBRO-PERC Soft Skills Training call of the International Brain Research Organization (IBRO) and the Pan-Europe Regional Committee (PERC). NEURODAT’21 is devoted to promote soft skills on entry level medicine and also STEMS area students interested on neurosciences. This part of the series focus the development of computational models in neurosciences, the use of these models to run simulations, the possibility of these simulations to become matrix-like worlds and/or the reachability of a self-awareness state by artificial intelligence computational models in the present and near future. Language note: English-Spanish bi-lingual talk and text.