The Human Immunodeficiency Virus has been
affecting people for years. Leading patients to
acquire several other diseases due to weakening
of the immune system. The use of metabolites
from marine algae have antiviral activities.
Therefore, this work analyzed among 40
molecules, originating from algae, through in
silico techniques, with the objective of proposing
a promising molecule with possible HIV
inhibitory activity.

The disease caused by the Human Immunodeficiency Virus (HIV) has infected people for over 50 years. Currently, 37.7 million people live with the virus, among these 150,000 people were infected with
the HIV virus only in the year 2020, in addition 73% of people use drug therapy with retrovirals.
Therefore, it is important to investigate new possible drugs, one of these ways is through computational
techniques.
The oceans have an enormous biodiversity, with biological sources rich in bioactive molecules,
since the pharmaceutical and cosmetic industries seek technological innovations, numerous marine
sources have been the object of study.
Among these are marine algae that are divided into macroscopic and microscopic. Both are rich
in secondary metabolites that have great pharmacological potential. Seaweeds already have several
studies on their broad biological activities such as: antimicrobial, anticancer, antiallergic, antioxidant,
anticoagulant, antidiabetic, antiparasitic, anti-inflammatory and antiviral.
Thus, this work aimed to analyze the possible inhibitory activity of molecules present in
seaweeds in proteins present in HIV.