Twenty EOs were examined for the first time against the Escherichia coli MS2 virus (surrogate of SARS-CoV-2). The most effective were the lemongrass (LGO), Niaouli (NO) and eucalyptus (ELO) with a virucidal concentration (VC) of 356.0, 365.2 and 586.0 mg/mL, respectively. PCL was processed via electrospinning, generating uniform, beadless fibrous mats. EOs loading was accomplished via (1) physisorption on pre-existing mats (PCLaEOs), and (2) blending with polymer solution prior to electrospinning (PCLbEOs). In both, 10% v/v VC was used. EOs presence and release was confirmed by UV-visible spectroscopy (≈5257-631 µg) and gas chromatography-mass spectrometry (≈14.3% EOs release over 4 h), respectively. PCLbEOs mats were mechanically and thermal resilient, with LGO promoting the strongest bonds with PCL (PCLbLGO). On the other hand, PCLaNO and PCLaELO were deemed the least cohesive combinations. EOs-loaded mats were identified as superhydrophobic. Air and water-vapor permeabilities were affected by the mats’ porosity (PCL<PCLaEOs<PCLbEOs). Antimicrobial testing revealed the mats’ ability to retain the virus and to inhibit its action. PCLbLGO was the most effective combination against MS2. These mats’ scent was also deemed the most pleasant. Overall, data demonstrated the potential of these EOs-loaded PCL fibrous mats to work as COVID-19 active barriers for individual protection masks. Other applications in individual protection equipment may also be envisaged, including disposable hospital gowns, head and shoe caps, etc.
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Essential Oils-Loaded Nanofibrous Mats for an Enhanced Protection against SARS-CoV-2
Published:
10 May 2022
by MDPI
in 3rd International Online-Conference on Nanomaterials
session Poster
Abstract:
Keywords: electrospun fibers; antiviral essential oils; physisorption versus blending; SARS-CoV-2 surrogate; viral inhibitors
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