Geophysical natural hazards, such as earthquakes and volcano eruptions, can have catastrophic effects on the population depending on the location and quality of construction. From the geophysical point of view, several aspects are still debated in the preparation phase of such events. In particular, several theories proposed that prior to the earthquake and volcano eruption, the releases of gas, fluids or charged particle from the lithosphere (e.g., the fault for the earthquake) could create some effects on the atmosphere and ionosphere. In this work, several single examples will be shown of possible candidates of pre-earthquake ionospheric disturbances recorded by the China National Space Administration (in partnership with the Italian Space Agency) China Seismo Electromagnetic Satellite (CSES) or European Space Agency Swarm constellation. The examples will show anomalous ionospheric status in terms of magnetic disturbances or increase of electron density before earthquakes like Mw=7.1 Ridgecrest (US) 2019 or during the large recent volcano eruption of Hunga Tonga-Hunga Ha’Apai of last 15 January 2022. In these cases, some couplings between the lithosphere and ionosphere are proposed. Finally, verifying if such ionospheric disturbances proceeded for “chance” or are really linked to the incoming event is a crucial point. For this purpose, we performed worldwide statistical studies, not only supporting the recurrence of such phenomena for about 15% of M5.5+ shallow earthquakes but also showing a link between the magnitude of the upcoming seismic events and the pre-earthquake anticipation time. Furthermore, we also show the influence of the location ( sea or land) on the frequency of the ionospheric electromagnetic disturbance.