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The potential application of Polymeric Nanoparticles in different cancer treatments
1  Department of Pharmacology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Biscay, Spain.
2  Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruña,Campus de Elviña, A Coruña, Spain.
Academic Editor: Humbert G. Díaz

Abstract:

Polymeric nanoparticles (NPs) are colloidal systems within the size range from 1 to 1000 nm where active agents are entrapped, dissolved, encapsulated or adsorbed onto the constituent polymeric matrix. These materials are important for biomedical applications and are frequently used as drug delivery systems (DDSs). Polymeric-based NPs could be used in cancer therapy, among others. This review will discuss the use of different polymeric NPs for various cancer treatments.

Keywords: polymers, nanoparticles, polymeric nanoparticles, biomedicine, drug delivery systems, cancer treatment
Comments on this paper
Shan He
Dear authors thank you for your support to the conference.
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Q. What role do the nanoparticles studied in this review play?

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Andrea Ruiz-Escudero
Dear Shan He,
Thank you for your attention to my work and for providing your valuable feedback.

In response to your question, the role of nanoparticles in cancer treatment varies according to the specific application. In general, nanoparticles can be utilized to deliver drugs, imaging agents, or heat to cancer cells in a precise manner.

On the one hand, Kong et al. utilized nanoparticles as part of a chemo-photothermal therapy strategy for breast cancer treatment. These nanoparticles were designed to deliver chemotherapy and heat simultaneously, accumulating at the tumor site and releasing the chemotherapy drug in a controlled manner, as well as being able to absorb laser light and generate heat to destroy cancer cells.

On the other hand, in the research conducted by Sanna et al., nanoparticles were used to deliver the anticancer compound EGCG to prostate cancer cells, enabling it to exhibit its antiproliferative effects in a targeted manner. These nanoparticles were designed to accumulate at the tumor site and release the EGCG in a controlled manner to optimize its therapeutic effect.

Lastly, similar to the previously mentioned research, the study conducted by Xin et al. utilized nanoparticles to deliver a therapeutic agent to glioma cells in a targeted manner. These nanoparticles were created to target and accumulate at the tumor site, releasing the therapeutic agent in a controlled manner to optimize its therapeutic impact.

Kind regards,
Andrea Ruiz Escudero



 
 
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