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Microwave-assisted Reactions of Substituted furo[3,2-b]pyrrole-5-carboxhydrazides and their Biological Activity
1 , 2 , 1 , 1 , * 1
1  Department of Chemistry, Faculty of Natural Sciences, University of St. Cyril and Methodius, Námestie Jozefa Herdu 2, Sk-917 01 Trnava, Slovakia
2  Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-2,

Abstract: The microwave-assisted reactions of substituted furo[3,2-b]pyrrole-5-carboxhydrazides 1 with 5-substituted furan-2-carboxaldehydes 2, thiophene-2-carboxaldehyde 3 and 2-formyl-4-methylfuro[3,2-b]pyrrole-5-carboxylate 4 have been studied under microwave irradiation. Reactions of 1 with 4-substituted 1,3-oxazol-5(4H)-ones 8 led to imidazole derivatives 9. The effects of hydrazones 5-7 on inhibition of photosynthetic electron transport in spinach chloroplasts were investigated.
Keywords: furo[3,2-b]pyrrole-5-carboxhydrazide, furan-2-carboxaldehyde, thiophene-2-carboxaldehyde, 2-formyl-4-methylfuro[3,2-b]pyrrole-5-carboxylate, microwave irradiation