Background: Hydrated fullerene C60FWS as an aqueous colloidal solution exhibits a wide range of biological activity at low concentrations.

Objective: The purpose of this study was the effect of hydrated fullerene nanoparticles on the safety of Pacific oysters (Crassostrea Gigas) during hypothermic storage.

Methods: Sensory characteristics, physicochemical and biochemical properties of the control without addition and the experimental one with the addition of 10^-8 M aqueous solution of C60FWS were used to assess the effect of hydrated fullerene nanoparticles on the preservation of oysters during storage at a temperature of 5°C.

Results: Monitoring the content of volatile nitrogenous compounds as accumulation products of protein degradation during autolytic and microbiological processes, water content in the muscle tissues, and also, changes in protein concentration as a criterion for a possible change in the adaptation processes of oysters during the storage time made it possible to establish significant differences for the control and experimental groups. It has been shown that these differences may indicate antioxidant properties. Changes in physicochemical and biochemical parameters correlate with changes in the organoleptic characteristics of oysters.

Conclusion: Preliminary storage of oysters in sea water with the addition of hydrated fullerene nanoparticles slows down the process of autolysis and allows it to be used as a tool to prevent changes in the quality of this food product, doubling the storage time of mollusks during transportation under anoxic and hypothermic conditions.