Please login first
New Bis-Urea Cross-Linking Monomers as Effective Oxyanion Receptors
, *
1  Department of Chemistry, Université de Montréal, C.P. 6128 Succursale, Centre-ville, Montréal, Québec, H3C 3J7, Canada

Abstract: A library of new polymerizable functional cross-linking monomers designed for complexation with the oxyanionic moiety of the chemotherapeutic drug methotrexate (MTX). The 1H NMR binding study of a variety of synthetic receptors and the compilation of the obtained results lead to the identification of monomers combining interactive functionality and a cross-linking format, specific binding receptors for dicarboxylate-containing drugs.