Events 9th International Electronic Conference on Medicinal Chemistry

Event submissions

Published

10.3390/ECMC2023-15642 (registering DOI)

This submission belongs to the session S4. New Small molecules as drug candidates of the event 9th International Electronic Conference on Medicinal Chemistry

Published date

01 Nov, 2023

Academic Editor

Alfredo Berzal-Herranz

Citation

Pietro Spanu, Ajay Chandgudge, Fausta Ulgheri, Giovanni Loriga, Maria Pia Fuggetta, Amalia M Dolga, Philip Hein Elsinga, Paula Kopschina Feltes, Erik FJ de Vries, Alexander Domling, <span>Design and Synthesis of a New Non-Covalent Caspase-3 Inhibitor with Neuroprotective Property</span>, in Proceedings of 9th International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2023, MDPI: Basel, Switzerland, doi: 10.3390/ECMC2023-15642

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Design and Synthesis of a New Non-Covalent Caspase-3 Inhibitor with Neuroprotective Property

Pietro Spanu ¹

Ajay Chandgudge ²

Fausta Ulgheri ¹

Giovanni Loriga ³

Maria Pia Fuggetta ⁴

Amalia M Dolga ⁵

Philip Hein Elsinga ⁶

Paula Kopschina Feltes ⁶

Erik FJ de Vries ⁷

Alexander Domling ^2,8

1. Istituto di Chimica Biomolecolare - CNR, Italy

2. Department of Drug Design, University of Groningen, Groningen, The Netherlands

3. Istituto di Chimica Biomolecolare - Consiglio Nazionale delle Ricerche, Italy

4. Istituto di Farmacologia Traslazionale - Consiglio Nazionale delle Ricerche, Italy

5. Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy, University of Groningen, The Netherlands

6. Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen

7. Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University

8. Palackӯ University, CATRIN, Department of Innovative Chemistry, Olomouc – Holice, Czech Republic;

Abstract

Keywords

Caspase-3 inhibitor

neuroprotective activity

Manuscript

Poster_Spanu.pdf

Poster

Poster_Spanu.pdf